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EC number: 203-624-3 | CAS number: 108-87-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96h) = 2.07 mg/L (Oryzias latipes, OECD 203, time weighted average concentration)
LC50 (96h) = 5.8 mg/L (Morone saxatilis, method similar to OECD 203, mean measured concentration)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.07 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 5.8 mg/L
Additional information
Three studies investigating the short-term toxicity of methylcyclohexane (CAS No. 108 -87 -2) to fish are available. Two studies were conducted by Japanese authorities using the freshwater species Oryzias latipes as test organism. The key study, was conducted under GLP conditions according to the Circular on Test Methods of New Chemical Substances (Japan), Fish, acute toxicity test (2005). This method is comparable to the OECD 203 (1992). A 96 h-LC50 value of 2.07 mg/L on the basis of time weighted average concentrations was determined for Oryzias latipes under semi-static test conditions. There was a significant loss of the test substance due to volatilisation during the preparation of test solution. Even if the test solutions were prepared freshly, the measured concentrations ranged approximately 30% of nominal. To minimize further substance losses during the test, the test was performed in a closed system without headspace. In this way, 82 – 101% of the initial measured concentrations remained stable during the 24 hour intervals.
A supporting study observed a similar LC50 value of 5.02 mg/L (nominal); however, using a shorter exposure time of 48 h (METI, 1986). A further study (Benville et al., 1985), which investigated the toxicity of the test substance to fish (Morone saxatilis) under marine conditions, determined a comparable 96h-LC50 of 5.8 mg/L (mean measured concentration).
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