Registration Dossier
Registration Dossier
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EC number: 231-442-4 | CAS number: 7553-56-2
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment:
The study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3 (Iodine has a low potential for bioaccumulation (log Pow = 2.49)
Bioaccumulation: terrestrial:
According Annex X 9.3.4 column 2 of Regulation 1907/ 2006 of the European Parliament and of the Council further testing for this endpoint is not considered to be necessary. Based on the log Pow of 2.49 only a low potential for bioaccumulation can be assumed. In addition, it's known that terrestrial plants metabolize iodine taken up from soil and wet deposition. But, findings in the public domain and in the soil migration study of Ashworth (endpoint 5.6) also indicate that no relationship between environmental concentrations of iodine and concentrations in plants exist.
Additional information
Iodine is present in all aquatic compartments and is known for its biological importance in animals and plants/algae. Thus, iodine trends to enrich in living organisms in higher concentrations as in the ambient (environmental) aquatic medium. In the report of the Agency for Toxic Substances and Disease Registry (ATSDR) of the U.S. Department of Health and Human Services several bioconcentration factors for iodine are summarized. Based on former studies these factors in fresh water are 40 (algae), 5 (invertebrates), and 15 (fish); in salt water, these factors are 4,000–10,000 (algae), 50–100 (invertebrates), and 10–20 (fish). Additionally, certain seaweeds and algae can concentrate iodine to levels as high as 0.8–4.5 g/kg of dried material; these high levels are usually associated with the relatively high levels of iodine in seawater (50 μg/kg). However, the exact physiological function and possible changes in speciation of iodine during the absorption and metabolism in different kinds of organisms are still quite unclear.
Based on the presented BCF values bioaccumulation in fish is not to be expected.
References:
Agency for Toxic Substances and Disease Registry (ATSDR). 2004. Toxicological profile for iodine.
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