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EC number: 232-395-2 | CAS number: 8013-75-0 A combination of amyl alcohols, primarily isoamyl alcohol and 2-methyl-1-butanol. Other alcohols, acids, esters and aldehydes may also be present.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC3/10 = 65 - 470 mg/L
EC50 > 1000 mg/L
Key value for chemical safety assessment
Additional information
Studies on the toxicity to microorganisms are available for two of the four main constituents of Fusel oil.
The key study available for 2 -Methylbutanol (CAS No. 137-32-6) was conducted according to the OECD Guideline 209 under GLP conditions (BASF, 2010). Activated sludge collected from a domestic sewage treatment plant was exposed to nominal test concentrations of 0, 62.5, 125, 250, 500 and 1000 mg/L in a dose-response test over 180 min. A positive control (3,5-dichlorophenol) was used in order to validate the test conditions. On the basis of respiration rate the effect concentrations were determined by measuring the CO2-evolution. At the end of the exposure period an EC50-value could not be calculated and it is considered to be > 1000 mg/L (nominal). The EC10 (180 min) was calculated to be 470 mg/L.
For Ethanol (CAS No. 64-17-5), a number of studies have been carried out to assess the toxicity of ethanol to microorganisms. In those studies ethanol has been tested on different freshwater protozoa and bacteria species. The study available forPseudomonas putida,which was performed according to DIN 38412, part 8 was chosen as key study (Bringman and Kuhn, 1978, 1980). In the dose-response test 14 concentrations were used which were not further specified. After a test duration of 72 h the toxicity threshold or EC3 was reported to be approximately 65 mg/L.
No studies on the toxicity to microorganisms are available for 3-Methylbutanol (CAS No. 123-51-3) and 2-Methylpropanol (CAS No. 78-83-1). 3 -Methylbutanol is structurally very similar to 2-Methylbutanol; both are branched primary aliphatic alcohols with five carbons. The structure of 2 -Methylpropanol only differs from 2 -Methylbutanol by the one carbon shorter chain length. The ecotoxicological profile is thus expected to be similar for the three constituents and thus effects of Fusel oil to microorganisms are not expected.
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