Registration Dossier
Registration Dossier
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EC number: 203-941-7 | CAS number: 112-16-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: no experimental data available.
Hydrolysis product lauric acid: Acutely harmful to aquatic algae after pH-adjustment.
Key value for chemical safety assessment
Additional information
Parent compound lauroyl chloride:
No experimental data are available for lauroyl chloride (CAS 112 -16 -3). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and lauric acid (CAS 112 -16 -3). Therefore, the short-term toxicity to aquatic algae and cyanobacteria is assessed on data for lauric acid (CAS 112 -16 -3) and its sodium salt (sodium laurate, CAS 629 -25 -4).
The toxic effect of the hydrolysis product lauric acid (CAS 143 -07 -7) was tested according to OECD 201 using Pseudokirchneriella subcapitata as the test species (NITE 2011,MOE 2012; test reported in 1999). The exposure period was 72 h. The 72 -h ErC50 was > 6.2 mg/L, the NOErC was 3.4 mg/L. In an ISO 8692 study with sodium laurate, the 72 -h ErC50 was determined to be 60 mg/L (Radix et al., 2000). The 72 -h EC10 was 1.1 mg/L, the NOEC 5 mg/L. Sodium laurate causes no shift in pH, therefore these effect values are comparable to data after neutralisation of the test solutions.
In conclusion, the lauroyl chloride and its hydrolysis product lauric acid are assessed to be acutely harmful to aquatic algae after pH-adjustment.
Hydrolysis product hydrochloric acid (HCl):
The hydrolysis product hydrochloric acid (HCl) was tested in an algae growth inhibition test according to OECD 201 withPseudokirchneriella subcapitata. The 72-h ErC50 was 0.492 mg/L (acid equivalent to pH 5.3), the 72 -h NOEC was 0.097 (acid equivalent to pH 6; OECD 2002).
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