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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: testing method performed according to OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
not specified
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chloro-2-nitroaniline
EC Number:
201-925-4
Cas Number:
89-63-4
Molecular formula:
C6H5ClN2O2
IUPAC Name:
4-chloro-2-nitroaniline

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.81
Temp.:
23 °C
pH:
ca. 7

Any other information on results incl. tables

Results in detail: Stock solution: 1032 mg/l

 determ. no. stock solution [ml] water [ml] test substance conc. in n-octanol phase [mg/l] test substance conc. in water phase [mg/l] log Pow 

A1

 25 10 1117,6 1,70 2,82
A2 5 10 1121,0 1,72 2,81
B1 10 10 1118,0 1,71 2,82
B2 10 10 1097,5 1,71 2,81
C1 20 10 1073,1 1,70 2,80
C2 20 10 1112,5 1,71 2,81
mean   --- --- --- --- 2,81

Applicant's summary and conclusion

Conclusions:
Due to the partition coefficient n-octanol-water of 2.81 at 23°C bioaccumulation is not expected.
Executive summary:

The partition coefficient n-octanol/water was determined according to OECD 107. The result was LogPow=2.81 at 23°C.