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Diss Factsheets
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EC number: 200-913-6 | CAS number: 75-89-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- density, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- Measurements were conducted with a method recommended in the current guidelines, and sounds of good scientific quality, however some informations are missing to allow full validation.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Type of method:
- oscillating densitimeter
- Key result
- Type:
- density
- Density:
- 1.383 g/cm³
- Temp.:
- 25 °C
- Executive summary:
The publication describes experimental density measurements, with oscillating densitimeter, of aqueous solutions of 2,2,2-trifluoroethanol varying from 0 to 100 %. For the pure substance, the result was found to be 1.3827 g/cm3 at 25°C. It is also pointed out that 2,2,2-trifluoroethanol has affinity with water vapor, so that exposure to air leads to rapid decrease of the density.
- Endpoint:
- density, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Type of method:
- pycnometer method
- Key result
- Type:
- density
- Density:
- 1.383 g/cm³
- Temp.:
- 298 K
- Remarks on result:
- other: (mole fraction = 1.0)
- Executive summary:
The densities of aqueous of solutions of 2,2,2-Trifluoroethanol, having a molar ratio ranging from 0.0365 to 1.0, were measured using a pycnometer method. At 25°C, the density of the pure alcohol was found to be 1.38335 g/cm3.
Referenceopen allclose all
Density of selected water-TFEtOH mixtures at 25°C
wt.% | Density (g/cm3) |
0,00 | 0,997070 |
9,97 | 1,032140 |
20,02 | 1,068590 |
30,01 | 1,105920 |
40,01 | 1,144380 |
49,98 | 1,181910 |
60,02 | 1,220900 |
70,01 | 1,261100 |
80,04 | 1,302740 |
90,03 | 1,339310 |
100,0 | 1,382710 |
The publication also provides a table with 25 density results for 0-1 mole fraction water-TFEtOH mixtures at 25°C.
The results of the present work on TFEtOH alone is also compared with litterature data:
°C | Density (g/cm3) | Ref. |
0,0 | 1,4106 | Janz 1972, Riddick 1986 |
22,0 | 1,3736 | Janz 1972, Riddick 1986 |
25,0 | 1,3826* | Evans 1971 |
25,0 | 1,38271* | this work |
* TFEtOH is highly hygroscopic and changes in density are observed when the liquid is not properly stored.
Data from different sources indicate a significant scattering on density values. In particular, the density of freshly distilled TFEtOH and of TFEtOH-rich solutions decreases when the samples are exposed to air. For instance, the freshly distillled fluorinated alcohol has a density of about 1.3827 g/cm3 at 25°C, which reduces to 1.3737 in a week, when the sample is kept in open air. Such behavior implies a strong affinity of TFEtOH for water vapor.
The densities of solutions in water are given in the following table:
Mole fraction | Density (g/cm3) |
0,0365 | 1,06117 |
0,0661 | 1,10279 |
0,130 | 1,16686 |
0,188 | 1,20925 |
0,271 | 1,25475 |
0,354 | 1,28551 |
0,519 | 1,32737 |
0,645 | 1,34837 |
0,773 | 1,36385 |
1,000 | 1,38335 |
Description of key information
Experimental results: 1.3827 g/cm3 (Gente 2000), 1.3834 g/cm3 (Rochester 1974).
Key value for chemical safety assessment
- Relative density at 20C:
- 1.383
Additional information
Two published experimental studies, conducted with oscillating densitimeter (1.3827 g/cm3) and pycnometer (1.3834 g/cm3), were considered reliable for the determination of the density.
Literature provides consistent data (1.362 to 1.39 g/cm3), except the Sax's handbook value, that was discarded, as considered inconsistent compared to the other results (1.288). Values from Baehr's publication were not taken into account as not suitable (pressure > ambient).
As the substance is known to absorb air moisture, the slightly higher mean of the two experimental results will be considered as the endpoint key value rather than the arithmetic mean of all retained values (1.381 g/cm3).
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