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EC number: 939-066-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- December 28, 1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 C(Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Initial biomass concentration: 30 mg/L
- Test type:
- other: Readily biodegradability
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Details on test conditions:
- TEST SYSTEM
Test equipment: Standard type.
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): BOD and test item concentration by GC.
TEST CONCENTRATIONS
- Test concentrations: 100 mg/L. - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The NOEC for microorganism toxicity of the test item sodium stearate was determined to be 100 mg/L under test conditions.
- Executive summary:
Based on the Readily Biodegradability test performed with sodium stearate according to OECD Guideline 301 C, where the substance was found to be readily biodegradable at 100 mg/L (28 days), the NOEC for microorganism toxicity is determined to be 100 mg/L since the compound degrades well.
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- December 16, 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 C(Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Initial biomass concentration: 30 mg/L
- Test type:
- other: Readily biodegradability
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Details on test conditions:
- TEST SYSTEM
Test equipment: Standard type.
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): BOD and test item concentration by GC.
TEST CONCENTRATIONS
- Test concentrations: 100 mg/L. - Reference substance (positive control):
- not specified
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The NOEC for microorganism toxicity of the test item docosanoic acid was determined to be 100 mg/L under test conditions.
- Executive summary:
Based on the Readily Biodegradability test performed with docosanoic acid according to OECD Guideline 301 C, where the substance was found to be readily biodegradable at 100 mg/L (28 days), the NOEC for microorganism toxicity is determined to be 100 mg/L since the compound degrades well.
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Principles of method if other than guideline:
- No data on experimental method.
- GLP compliance:
- not specified
- Remarks:
- (no data on GLP)
- Analytical monitoring:
- not specified
- Vehicle:
- yes
- Details on test solutions:
- 15% propylen glycol and 34-37% water
- Test organisms (species):
- Pseudomonas putida
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 17 h
- Duration:
- 17 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 580 mg/L
- Key result
- Duration:
- 17 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 890 mg/L
- Duration:
- 17 h
- Dose descriptor:
- other: EC90
- Effect conc.:
- > 1 200 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 17 hour exposure EC10, EC50 and EC90 for ammonium propionate to Pseudomonas putida were determined to be >580 mg/L, >890 mg/L and >1200 mg/L.
- Executive summary:
The 17 hour exposure EC10, EC50 and EC90 for ammonium propionate to Pseudomonas putida were determined to be >580 mg/L, >890 mg/L and >1200 mg/L.
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No guideline was followed. No data on GLP.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test: The inhibitory effect of sodium palmitate on the oxygen uptake rate of activated sludge was investigated by the use of the oxygen electrode method.
- GLP compliance:
- not specified
- Test organisms (species):
- activated sludge
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Key result
- Duration:
- 96 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 2 500 mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The inhibitory effect of sodium palmitate on the oxygen uptake rate of activated sludge was investigated by the use of the oxygen electrode method. The IC50 -96h was determined to be >2500 mg/L.
- Executive summary:
The inhibitory effect of sodium palmitate on the oxygen uptake rate of activated sludge was investigated by the use of the oxygen electrode method. The IC50 -96h was determined to be >2500 mg/L.
Referenceopen allclose all
Test item sodium stearate was readily biodegradable under test conditions.
BOD (28 days): 83% degradation
Test material analysis by GC (28 days): 100% degradation.
Test item sodium stearate was readily biodegradable under test conditions.
BOD (28 days): 51% degradation
Test material analysis by GC (28 days): 73% degradation.
In a parallel inherent degradation test was performed for 4 weeks in an open system (test substance: 30 mg/L, activated sludge: 100 mg/L) and the % degradation was determined to be 95% (test item measured by GC)
The 17 hour exposure EC10, EC50 and EC90 for ammonium propionate to Pseudomonas putida were determined to be >580 mg/L, >890 mg/L and >1200 mg/L.
Description of key information
Weight of evidence: Based on the experimental results obtained with the analogue substance, the weight of evidence approach was applied and the NOEC for microorganism toxicity for the substance Fatty acids, C16-18 (even numbered), ammonium salts was determined to be 100 mg/L (worst case assumption).
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Weight of Evidence Approach (see rationale attached in IUCLID5 Section 13):
According to Verschueren K (2009), the 17 hour exposure EC10, EC50 and EC90 for ammonium propionate to Pseudomonas putida were determined to be >580 mg/L, >890 mg/L and >1200 mg/L.
In a study reported by Mihara Y et al. (1992), the inhibitory effect of sodium palmitate on the oxygen uptake rate of activated sludge was investigated by the use of the oxygen electrode method. The 96h-IC50 was determined to be >2500 mg/L.
Based on the Readily Biodegradability test performed by MITI according to OECD 301 C, sodium stearate was exposure to activated sludge for 28 days and the substance was found to be readily biodegradable at a concentration of 100 mg/L. Therefore, the NOEC for microorganism toxicity is determined to be 100 mg/L since the compound degrades well.
In the same way a Readily Biodegradability test was performed by MITI according to OECD 301 C on docosanoic acid. Activated sludge was exposed to the test item for 28 days and the substance was found to be readily biodegradable at a concentration of 100 mg/L. Therefore, the NOEC for microorganism toxicity is determined to be 100 mg/L since the compound degrades well.
Taking into account the available experimental results, the weight of evidence approach was applied and the NOEC for toxicity to microorganisms for the substance Fatty acids, C16 -18 (even numbered), ammonium salts was determined to be 100 mg/L (based on the worst case assumption.
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