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EC number: 293-316-5 | CAS number: 91053-50-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7860 (Water Solubility Generator Column Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- other: generator column method
- Water solubility:
- < 1 mg/L
- Temp.:
- 20 °C
- pH:
- 8
- Details on results:
- An organic carbon background was evident in the bottled reagent water used for this work. A reagent water screen demonstrated that this background was evident in subsequent additional aliquots from the same and aliquots from different lots. Background levels were approximately half that of the low-level calibration standard. Therefore, the background was considered significant and was used to correct the measured TOC in the test samples (background subtraction). The temperature of the water bath remained constant at 20.0 ± 0.1°C throughout the experiment. Under the instrumental conditions presented, mean measured reagent water solubility for the test substance at 20°C was 0.5 ± 0.1 mg C/L (CV =24%, n = 5) at a flow rate of approximately 1.0 mL/min and was 0.48 ± 0.02 mg C/L (CV =5.1%, n = 5) at a flow rate of approximately 0.50 mL/min. The mean test substance concentration for the 1.0 and 0.50 mL/min flow rate settings differed by 6.65%, which was well within the ± 30% test criterion. The overall mean measured water solubility for the test substance at 20°C was 0.49 ± 0.09 mg C/L (CV = 17%, n = 10). Since this value is less than the limit of detection (1 mg/L), the final results will be reported as < 1 mg/L. The pH of the test samples was evaluated concurrent with the definitive solubility trial. All of the test samples had a measured pH of 8.
- Conclusions:
- The water solubility of the test substance in reagent water at 20ºC was determined using the generator column method. The net (background subtracted) solubility of the test substance was less than the limit of quantification of 1 mg C/L for TOC analysis.
- Executive summary:
The water solubility of the test substance was determined in reagent water at 20°C using the generator column method. Solubility samples were collected and analyzed using total organic carbon analysis (TOC). The net (background subtracted) solubility of the test substance was less than the limit of quantification of 1 mg/L for TOC analysis.
Reference
Description of key information
OECD Guideline 105
Water solubility is < 1 mg/L
Key value for chemical safety assessment
- Water solubility:
- 1 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.