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EC number: 235-471-3 | CAS number: 12238-31-2 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 15860:2.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Nanomaterial dustiness
Administrative data
- Endpoint:
- nanomaterial dustiness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EN 17199-4
- Version / remarks:
- 2019-03
- Principles of method if other than guideline:
- EN 17199-4:2019-03
Workplace exposure — Measurement of dustiness of bulk materials that contain or release nano-objects or submicrometer particles — Part 4: Small rotating drum method. - GLP compliance:
- no
- Type of method:
- other: Small Rotating Drum
- Details on methods and data evaluation:
- 3.4 Detection methods
3.4.1 Mass-based dustiness index
The mass-based dustiness index is determined gravimetrically. The filter in the cyclone is measured before and after the rotation of the drum. The results are given as average of the triplicate, and its standard deviation.
3.4.2 Number-based dustiness index
The number-based dustiness index is determined by the Condensatino Particle Counter (CPC). The filter in the cyclone is measured before and after the rotation of the drum. The results are given as average of the triplicate, and its standard deviation.
3.4.3 Size distribution of the aerosol
The size distribution is determined by weighing the impactor stages (MOUDI) before and after the complete set of triplicate rotations, because a single rotation of many materials does not deposit enough dust on each individual impactor stage. The results thus reflect the average of the triplicate.
3.4.4 Morphology of the aerosol
Non-mandatory, the aerosol can be collected on porous Gold filters for analysis of the identity and morphology of the airborne particles by Scanning Electron Microscopy (SEM). This option was not performed in the present case, because the test item is a pure substance with no uncertainty on the identity of aerosols.
Test material
- Reference substance name:
- Manganese, 4-[(4-chloro-5-methyl-2-sulfophenyl)azo]-3-hydroxy-2-naphthalenecarboxylic acid complex
- EC Number:
- 235-471-3
- EC Name:
- Manganese, 4-[(4-chloro-5-methyl-2-sulfophenyl)azo]-3-hydroxy-2-naphthalenecarboxylic acid complex
- Cas Number:
- 12238-31-2
- Molecular formula:
- C18H11N2O6SClMn
- IUPAC Name:
- 10-carboxy-18-chloro-19-methyl-15,15-dioxo-12λ³,14λ³-dioxa-15λ⁶-thia-1λ⁴,22-diaza-13-manganapentacyclo[11.9.0.0²,¹¹.0³,⁸.0¹⁶,²¹]docosa-1(22),2(11),3,5,7,9,16,18,20-nonaene-13,13-bis(ylium)-12,14-diide
- Test material form:
- solid: nanoform
Constituent 1
Data gathering
- Instruments:
- Small Rotating Drum (SRD)
The powder is loaded into the drum and is evenly spread on one of the lamellae that lift the powder during rotation. One “conditioning” run coats the inner surface of the drum, and is not used for data acquisition (Schneider and Jensen 2008).
Then, the three replicate measurements are each performed with fresh powder. Particle-free air is flushed through the drum at standstill, and the aerosol concentration is monitored by the CPC until the background (here: 13 particles /mL, indicating a very airtight setup) is reached. Then, the drum is rotated for 60 seconds. This rotation event results in a peak aerosol concentration in the CPC, and deposits dust onto the filter after the cyclone, and onto the MOUDI impactor stages. When the concentration has fallen after stopping the drum, the drum is removed, powder exchanged, and the next replicate taken.
The speed of rotation is 11 rpm as given for the SRD in the revised CEN standard.
Results and discussion
Dustiness index
- Key result
- Mean:
- 44 mg/kg
- St. dev.:
- 11.7 mg/kg
- Remarks on result:
- other: respirable dustiness mass fraction
Any other information on results incl. tables
The average respirable mass-based dustiness of 44 ± 11.7 mg/kg places the Pigment Red 52:2 into the band of low dustiness.
As far as we know, no fixed bands have been established for the number-based dustiness index.
Comparing to academic data on other fillers and pigments, the average number-based dustiness index of 0.56±0.005 * 104mg-1is relatively low.
Consistently with the average values, the size distribution of the aerosol indicates significant agglomeration with polydisperse aerodynamic diameters, peaking at 5.6 µm.
Applicant's summary and conclusion
- Conclusions:
The average respirable mass-based dustiness of 44 mg/kg places the Pigment Red 52:2 into the band of low dustiness.
The average number-based dustiness index was found at 5600/mg.
The size distribution of the aerosol indicates significant agglomeration with polydisperse aerodynamic diameters, peaking around 5.6 µm.
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