Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 293-426-3 | CAS number: 91079-38-8
Endpoint summary
Administrative data
Description of key information
2 reliable studies on skin irritation for Protein Hydrolysates animal show no irritation effects on rabbit and human skin. A Bovine Corneal Opacity and Permeability Test was conducted for Peptones Beef and it showed no corrosive or irritant effects on the eyes. Based on these results, Peptones Beef is not expected to show skin and eye irritating effects.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
2 reliable studies on skin irritation for Protein Hydrolysates animal show no irritation effects on rabbit and human skin. Based on a read across approach from a similar substance, Peptones Beef is not expected to show skin irritating effects.
A Bovine Corneal Opacity and Permeability Test which was conducted on Peptones Beef according to OECD guideline 437 showed a very low in vitro irritancy score enough to not classify as eye irritant.
Justification for classification or non-classification
As all reliable studies show no irritation effects, Peptones Beef do not need to be classified as irritant for skin and eye according to the criteria of Annex VI of Directive 67/548/EEC and CLP Regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
