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EC number: 937-237-2 | CAS number: 1370006-50-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 63d NOEC of >100 μg/L was determined in a 21-day-reproduction test with Daphnia magna over 3 generations. Daphnids were exposed to the effluent of the activated sludge unit containing the degradation products of partially unsaturated IQAC, DMS quaternised.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 µg/L
Additional information
The 21-day-reproduction test of the effluent of a model activated sludge unit fed with 10 mg/L partially unsaturated IQAC (containing 10% of Isopropanol) to Daphnia magna was studied under static renewal conditions. Daphnidswere exposed to the effluent of the activated sludge unit containing the degradation products of the test item. A control activated sludge unit without the test item was run in parallel. The test duration for every generation was 21 days. Neonates of the 14thtest day were exposed as filial generation under the same conditions as the parental generation. Filial generations 1 and 2 were monitored for reproduction rate, time of the first offspring and parental mortality.
Parental generation: In the parental generation there was no difference between the exposed and the not exposed daphnids, however the first offspring in the controls was one day later. Mortality of the parental generation was slightly higher in the control.
F1 generation:
42 days after the start of exposition of parental generation, the reproduction rate of the surfactant exposed F1 generation was enhanced and exceeded that of the control. The mean number of parental daphnids was greater than in the control. There was no difference in the time of appearance of the first offspring. Mortality of the parental generation was slightly higher in the control.
F2 generation:
63 days after the start of exposition of the first parental generation, in the second filial generation some adverse effects were observed for the surfactant exposed Daphnids: Growth rate decreased and the size and colour of the control animals were not reached. The reproduction rate was significant lower than in the parental generation and the F1 generation. The mortality of the parental animals increased. During the test, partially unsaturated IQAC, DMS quaternised, is eliminated in the model activated sludge unit by > 90%. The elimination is calculated to be 97.75% taking into account the inflow into the model activated sludge unit of the test substance with a concentration of 10 mg/l, the dilution of the effluent of the elimination unit in ratio 1:1.25 and the separately determined EC0=0.1 mg/l to Daphnia magna. Thus a NOEC of >100 μg/L is calculated.
The test material contains isopropanol. The toxicity of isopropanol against Daphnia magna is more than 10 000 times lower than the toxicity of the test material.Water solubility of the test item may be slightly enhanced leading to a better bioavailability and slightly enhanced toxicity. But these effects are regarded to have a minor influence on the test result.Therefore it can be concluded in a first approach, neglecting additive effects, that the observed effect values can be attributed to the active ingredient itself.
This study is classified as acceptable and satisfies basic scientifically requirements for a chronic toxicity study with freshwater invertebrates, although not all data were reported.
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