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Diss Factsheets
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EC number: 454-800-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosive properties of explosives
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 113 (Screening test for thermal stability and stability in air)
- GLP compliance:
- yes (incl. QA statement)
- Parameter:
- thermal sensitivity - Koenen test: diameter of the orifice plate
- Remarks on result:
- not thermal sensitive if heated under defined confinement
- Parameter:
- sensitiveness to friction: friction load (N)
- Remarks:
- migrated information
- Remarks on result:
- not sensitive to friction using a friction load of 360 N
- Parameter:
- sensitiveness to impact: impact energy (J)
- Remarks on result:
- not sensitive to impact using an impact energy of 40 J
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 2-Chloro-5-chloromethylpyridine has no danger of explosion according to the explosive properties in the sense of the consolidated version of Council Directive 67/548/EEC Annex V, A. 14.
- Executive summary:
The explosive properties of 2 -chloro-5 -chloromethylpyridine were tested according to EU test method A.14. As a sceening test the thermal stability according to OECD 113 was performed.
The determination of the thermal stability was carried out by differential scanning calorimetry (DSC). The test item and the standard material in closed glass crucibles were heated up from ambient temperature to the final temperature (500 °C) at a constant heating rate (3 K/min) in a defined atmosphere (nitrogen).
Thermal Sensitivity
The method involves heating the substance or preparation in a steel tube, with various degrees of confinement being provided by nozzle-plates with a diameter (2 mm) of orifice, to determine whether the substance or preparation is liable to explode under conditions of thermal stress.
Mechanical Sensitivity (Shock)
The method involves subjecting the substance or preparation to the shock of a falling hammer on a steel anvil. The test was performed with the powdered and sieved (< 500 µm) test item.
Mechanical Sensitivity (Friction)
The method involves subjecting the substance or preparation to friction between standard surfaces under specified conditions of load and relative motion. This test is restricted to solid and pasty substances or preparations. The test was performed with the powdered and sieved (< 500 µm) test item.
2-Chloro-5-chloromethylpyridine has no danger of explosion according to the explosive properties in the sense of the consolidated version of Council Directive 67/548/EEC Annex V, A. 14.
Reference
Description of key information
The explosive properties of 2 -chloro-5 -chloromethylpyridine were tested according to EU test method A.14. As a sceening test the thermal stability according to OECD 113 was performed.
The determination of the thermal stability was carried out by differential scanning calorimetry (DSC). The test item and the standard material in closed glass crucibles were heated up from ambient temperature to the final temperature (500 °C) at a constant heating rate (3 K/min) in a defined atmosphere (nitrogen).
Thermal Sensitivity
The method involves heating the substance or preparation in a steel tube, with various degrees of confinement being provided by nozzle-plates with a diameter (2 mm) of orifice, to determine whether the substance or preparation is liable to explode under conditions of thermal stress.
Mechanical Sensitivity (Shock)
The method involves subjecting the substance or preparation to the shock of a falling hammer on a steel anvil. The test was performed with the powdered and sieved (< 500 µm) test item.
Mechanical Sensitivity (Friction)
The method involves subjecting the substance or preparation to friction between standard surfaces under specified conditions of load and relative motion. This test is restricted to solid and pasty substances or preparations. The test was performed with the powdered and sieved (< 500 µm) test item.
2-Chloro-5-chloromethylpyridine has no danger of explosion according to the explosive properties in the sense of the consolidated version of Council Directive 67/548/EEC Annex V, A. 14.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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