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EC number: 241-793-5 | CAS number: 17832-28-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
For 4 -(vinyloxy)butan-1 -ol a STP sluge respiration pre-guideline study is available which was however performed according to a method equivalent to OECD TG 209 (BASF, 1988). In this study a laboratory culture prepared from sludge taken from BASF sewage treatment plant was inoculated with nominal test substance concentrations of up to 1000 mg/L for a period of 30 minutes (reduced exposure period as volatilisation was expected to occur). Throughout the test a slight increase rather than decrease of respiration was recorded. based on these findings, the 30 -min NOEC in STP sluge is determined at ≥1000 mg/L. No detail is provided on whether the activated sludge used was or was not pre-exposed (i.e. adapted). However, based on the overall available data and consequent assessment of the biodegradation of 4 -(vinyloxy)butan-1 -ol, no significant toxicity to aquatic microorganisms is to be expected. Therefore the NOEC of 1000 mg/L is used for calculation of the PNECstp.
The afore stated is further supported by a test with the analogous substance isobutyl vinyl ether (CAS 109 -53 -5) which was conducted according to German Industrial Standard DIN 38412 part 27 (Robra-Test) (BASF, 1988). In this study bacteria cultures (P. putida) were exposed to test concentrations in the range of 1250 -10000 mg/L for a period of 17 hours. Based on the recorded oxygen consumption, an 17 -h EC10 of 3376 mg/L was determined. According to REACH guidance, data obtained with Pseudomas tests should be considered for assessment only when no other data is available. As other data is available, this data is considered as supporting information only.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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