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EC number: 205-187-4 | CAS number: 135-37-5
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No data for EDG are available. However, Arthur et al (1974) presents 32 week NOEC results of >54 mg/L with the structurally comparable NTA for survival and reproduction for the fathead minnow, Pimephales promelas. Recalculated to EDG (mol weight ratio) would give > 43.4 mg/L EDG (molweight EDG/NTANa3.H20 = 221/275 x 54).
Key value for chemical safety assessment
Additional information
Arthur et al (1974) presents 32 week NOEC results of >54 mg/L NTA for survival and reproduction for the fathead minnow, Pimephales promelas. Study was performed by exposing 3 -15 day old fry to measured concentrations of NTA for 32 weeks. Mortality, spawing activity and hatchability were assessed. The F1 generation was exposed for 30 days to NTA and growth assessed. A 30 day NOEC of > 60.2 mg/L was presented for the growth rate of the F1 generation.
The 32 week NOEC would correspond to > 43.4 mg/L EDG and as it indicated as '>' value it can not be given in the box above.
Birge et al. (1979) exposed rainbow trout embryos for 27 days (4 days post-hatch) to measured concentrations of NTA at two different hardnesses. Mortality was assessed at hatch and 4 days post-hatch. The27 day LC50 for 50 mg/L hardness test = 90.5 mg/L and, for 200 mg/L hardness test the LC50 = 114 mg/L. This study is considered supporting.
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