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EC number: 226-540-9 | CAS number: 5421-46-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Determination of the reaction rate for the oxidation of ATG in aereated water by HPLC
- GLP compliance:
- no
- Remarks:
- The central laboratory was quality audited regarding ISO 9001:2000 by TÜV-Cert in June 2007, audit May 2009.
Test material
- Reference substance name:
- Ammonium mercaptoacetate
- EC Number:
- 226-540-9
- EC Name:
- Ammonium mercaptoacetate
- Cas Number:
- 5421-46-5
- Molecular formula:
- C2H4O2S.H3N
- IUPAC Name:
- ammonium 2-sulfanylacetate
- Details on test material:
- - Name of test material (as cited in study report): Ammonium thioglycolate 71%
- Physical state: liquid
- Analytical purity: 71.26 (iodometric)
- Lot/batch No.: 790000007017
Constituent 1
Results and discussion
Any other information on results incl. tables
Results
In aerated tap water of Marschacht community (which corresponds to natural occuring surface and ground water) the degradation down to non detectable concentrations of the test material took place in two hours. The concentration of oxidation product diammonium dithiodiglycolate (DADTDG) was measured to 72.0% of the theoretical amount.
Discussion
In aerated tap water - which is comparable to ground water and surface water - the oxidation of the test material was completed after 2 hours with the theoretical amount of 72.0 % of oxidation product detected. The first step of oxidation took place during the preparation of the sample at start point. After one hour ongoing oxidation another unidentified product evolved at later retention time than dithiodiglycolate. The pH value rose with ongoing oxidation staying constant after 24 hours. The unidentified peak is very broad, this is a hint to an alkaline substance. Plotting peak area% against time (pic.9) shows, that this product disappears as well, but slowlier than thioglycolate. The evolving small unidentified peaks at higher retention times are disregarded because of their negligible magnitude.
Applicant's summary and conclusion
- Conclusions:
- The velocity of degradation of thioglycolate anion in oxygen saturated tap water was such high, that the first sample taken at start point showed already considerable amount of oxidation product. 2 hours later thioglycolate was no longer detectable. The amount of oxidation product increased to 72.0 % of theoretical amount. The evolving product at 6.25 min retention time decreased to 21% of the highest value after 4 days. The estimated t1/2 is 30 h, that means after 12 days this degradation product will be no longer detectable.
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