Registration Dossier
Registration Dossier
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EC number: 221-259-8 | CAS number: 3048-64-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Vinyl norbornene (VNB) has been investigated in in vitro tests, and did not induce gene mutation in bacterial or mammalian systems or in a sister chromatic exchange assay in cultured cells, with or without an exogenous metabolic activation system. In addition, an in vivo chromosome abberation test in rats was negative.
Short description of key information:
VNB was not mutagenic with and without an exogenous metabolic activation system in bacteria and mammalian cells in vitro and in vivo.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
On the basis of reliable negative studies no classification is proposed.
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