Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
flammability
Type of information:
experimental study
Adequacy of study:
other information
Study period:
15 July 2009-4 August 2009
Reliability:
3 (not reliable)

Data source

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The substance is formed into an unbroken strip or powder train about 250 mm long and a preliminary screening test performed to determine if, on ignition by a gas flame , propagation by burning with flame or smoldering occurs. If propagation over 200 mm of the train occurs within a specified time, a full test program to determine the burning rate is carried out.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
(2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
EC Number:
700-456-7
Cas Number:
1333490-26-8
Molecular formula:
C26H31Cl2N5O4 · 1/2(C3H8O1)
IUPAC Name:
(2E)-2-cyano-N-(2,4-dichloro-5-methoxyphenyl)-3-({4-methoxy-3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}amino)prop-2-enamide; propan-2-ol
Details on test material:
Molecular weight: 548.47
Batch: 09-002
Purity: >92% (Contains 6.5% isopropanol as a hemi-solvate
Appearance: Yellowish solid

Results and discussion

Any other information on results incl. tables

The powder melted and ignited at the point where the flame was applied, however, the fire did not spread beyond that point . The substance 3508 is not a highly flammable solid.

Applicant's summary and conclusion