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Diss Factsheets
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EC number: 939-717-7 | CAS number: 1474044-79-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: An appropriate number of animals were exposed to a concentration (~18 mg/L) greatly exceeding the standard limit concentration (5 mg/L).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 978
- Report date:
- 1978
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: FHSLA, CFR, Title 21 J para. 191.10.
- Deviations:
- not specified
- GLP compliance:
- no
- Test type:
- fixed concentration procedure
- Limit test:
- yes
Test material
- Reference substance name:
- Calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalene sulphonate)
- Molecular formula:
- [C26H39SO3]2Ca to [C30H47SO3]2Ca
- IUPAC Name:
- Calcium bis(di C8-C10, branched, C9 rich, alkylnaphthalene sulphonate)
- Test material form:
- liquid: viscous
- Details on test material:
- A dark brown viscous liquid identified as NASUL 729
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- A group of five male and five female Wistar rats were exposed to the test
material.
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- whole body
- Vehicle:
- not specified
- Details on inhalation exposure:
- Rats were exposed to NASUL 729 (vaporized) in an inhalation chamber for 1 hour. The chamber was saturated with
18 mg/liter nominal of the test material prior to the period of exposure.
The rats were observed for 14 days following exposure. Feed and water were provided ad libitum. - Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- ca. 1 h
- Concentrations:
- 18 mg/liter nominal
- No. of animals per sex per dose:
- 5 male and 5 female rats
- Control animals:
- no
- Statistics:
- None required. No mortality.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 18 mg/L air (nominal)
- Based on:
- test mat.
- Exp. duration:
- 1 h
- Mortality:
- No mortality.
- Clinical signs:
- other: No untoward reactions.
- Body weight:
- See table.
- Gross pathology:
- None reported.
Any other information on results incl. tables
Rat No. |
Sex |
Body Weight - grams |
Mortality |
1 |
M |
229 |
No |
2 |
M |
265 |
No |
3 |
M |
229 |
No |
4 |
M |
256 |
No |
5 |
M |
263 |
No |
6 |
F |
291 |
No |
7 |
F |
271 |
No |
8 |
F |
256 |
No |
9 |
F |
261 |
No |
10 |
F |
278 |
No |
Applicant's summary and conclusion
- Interpretation of results:
- other: relatively harmless
- Conclusions:
- The Inhalation LC50 of rats exposed for 1 hour to the test material is greater than 18 mg/liter.
- Executive summary:
A group of five male and five female Wistar rats were exposed to NASUL 729. The rats were exposed to NASUL 729 (vaporized) in an inhalation chamber for 1 hour. The chamber was saturated with 18 mg/liter nominal of the test material prior to the period of exposure. The rats were observed for 14 days following exposure. Feed and water were provided ad libitum. No mortalities or clinical symptoms observed. The Inhalation LC50 of rats exposed for 1 hour to the test material is greater than 18 mg/liter. On an active ingredient basis the LC50 > 9 mg/L.
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