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EC number: 691-657-8 | CAS number: 62599-49-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study without restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-(2-methylprop-2-en-1-yl)cyclododecan-1-one
- EC Number:
- 691-657-8
- Cas Number:
- 62599-49-9
- Molecular formula:
- C16 H28 O
- IUPAC Name:
- 2-(2-methylprop-2-en-1-yl)cyclododecan-1-one
- Details on test material:
- - Name of test material (as cited in study report): 2-(2-Methylallyl)-cyclododecanon-Rein
- Physical state: liquid / colorless, clear
- Analytical purity: 94-99%
- Lot/batch No.: (MACD Probe aus B410.16 vom 04.10.2012) xxxxxxxxxxx
- Storage condition of test material: Storage at room temperature
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Municipal activated sludge from the wastewater treatment plant of Mannheim, Germany
- Storage conditions: The inoculum was collected from the aeration tank of the plant and aerated in the laboratory until use. A suitable aliquot of the activated sludge suspension was sieved by a finely woven mesh with a mesh size about 1 mm. To reduce the content of inorganic carbon in the blank controls the activated sludge suspension was pre-aerated for about 24 hours with synthetic air at a temperature of 22 ± 2 °C.
- Preparation of inoculum for exposure: At the day of exposure the suspension was washed one time with tap water. Therefore the aeration was stopped and the sludge was allowed to settle. After settling the supernatant was discarded and the remaining sludge suspension was filled up with tap water and the concentration of the sludge was adjusted to 6.0 g/L dry weight.
- Pretreatment: none
- Concentration of sludge:
Aliquots of 7.5 mL was added to the test vessels to obtain a sludge concentration of 30
mg/L dry weight. - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 25 mg/L
- Based on:
- test mat.
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to guideline
- Solubilising agent (type and concentration if used): no
- Test temperature: 22 ± 2 °C
- pH: The pH-values in the test vessels were measured and adjusted to 7.4 ± 0.2, if necessary
TEST SYSTEM
- Culturing apparatus: 2 L incubation bottles
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: pre-aeration for two days before test start
- Measuring equipment: carbon dioxide trap
- Details of trap for CO2 and volatile organics if used: Usually twice a week the Total Inorganic
Carbon (TIC) values of the adsorption solutions of the first trap were determined and
used for the calculation of the produced carbon dioxide. After each sampling the second
trap was moved forward and the new trap with fresh sodium hydroxide solution was
placed into the second position. Each trap was analyzed separately
- Test performed in open system: no
SAMPLING
- Sampling frequency: Usually twice a week
Samples for the TIC- and DOC-analysis were performed as repeat determination, using a
TOC-analyzer equipped with an auto sampler (Shimadzu TOC-5000A). The system works
with a combustion/non-disperse infrared gas analysis method.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Inhibition control: yes
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- < 10
- Sampling time:
- 28 d
- Details on results:
- 2-(2-Methylallyl)-cyclododecanon-Rein was not readily biodegradable under the conditions of this test.
BOD5 / COD results
- Results with reference substance:
- Degree of biodegradation of the reference substance after 14 days: 69 % CO2/ThCO2
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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