Registration Dossier
Registration Dossier
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EC number: 204-875-1 | CAS number: 128-03-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (21d, reproduction) = 78 µg a.i./L (Daphnia magna)
Key value for chemical safety assessment
Additional information
No information about the chronic toxicity of KDDC (CAS No. 128-03-0) to aquatic invertebrate species was available. Therefore, a conclusion about this endpoint had to be drawn based on toxicity data from an analogue substance. The chronic toxicity of Ziram (CAS No. 137-30-4) to Daphnia magna was investigated by Palmer et al. (2006). This test was performed according to OECD Guideline No. 211, Daphnia magna Reproduction Test (1998) and EPA OPPTS 850.1300, Daphnid Chronic Toxicity Test (1996), under GLP conditions. Daphnids were exposed for 21 days to the test substance within a flow-through water regime. Adverse effects on growth, survival and reproductive performance (measured as number of neonates per female) were reported, resulting in a NOEC of 78 µg a.i./L (based on reproduction).
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