Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-617-2 | CAS number: 97-90-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-01-13 to 2012-02-10
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD 301 F, GLP. The 10-day-window was not passed.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- adoped July 17, 1992
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Version / remarks:
- of May 30, 2008 (EEC Publication No. L 142/496, May 2008)
- Principles of method if other than guideline:
- The biodegradation of organic compounds is determined by the determination of oxygen consumption of microorganisms using a manometric
respiratory test over a period of 28 days. - GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Ethyleneglycol dimethacrylate
- Substance type: organic
- Physical state: liquid - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Source of inoculum/activated sludge: Aerobic activated sludge (micro-organisms from a domestic wastewater treatment plant) was supplied by the sewage works of Rossdorf, Germany.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 102 mg/L
- Based on:
- ThOD/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 21-22 °C
- pH: 7.6 at study start, 6.8 - 7.6 at the end of the test
- pH adjusted: no
- Suspended solids concentration: 1.5 dry material per litre
- Continuous darkness: yes
TEST SYSTEM
- Measuring equipment: BSB Sensomat system, Aqualytic Dortmund, Germany
- Test performed in closed vessels due to significant volatility of test substance: flasks were closed gas-tight
- Details of trap for CO2 and volatile organics if used: aqueous solution of potassium hydroxide (45%) was used for trapping the produced CO2
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes, poisoned with HgCl2 (stock solution of 48.84 mg/mL)
- Toxicity control: Ethyleneglycol dimethacrylate and the reference substance - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 69
- Sampling time:
- 28 d
- Remarks on result:
- other: 10-d window was not reached
- Parameter:
- % degradation (O2 consumption)
- Value:
- >= 30 - <= 33
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 45
- Sampling time:
- 10 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- >= 50 - <= 53
- Sampling time:
- 15 d
- Details on results:
- Biodegradation of the reference substance sodium benzoate: Sodium benzoate was sufficiently degraded to 85 % after 14 days and after 28 days of
incubation. Therefore it was concluded that the aerobic activated sludge inoculum used was suitable for the test.
Biodegradation of the toxicity control: Toxicity control containing both, Ethyleneglycol dimethacrylate and the reference substance, 58 % biodegradation was noted within 14 days and 62 % biodegradation after 28 days of incubation.
Ethyleneglycol dimethacrylate was therefore not inhibitory to the aerobic activated sludge micro organisms.
Abiotic control: The oxygen demand in the abiotic control was zero. No correction of the test item degradation rates had to be done. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- A degradation rate of 69 % was obtained after 28 days, thus the test substance Ethylene glycol dimethacrylate has to be classificated as readily biodegradable, but failing 10-day window.
- Executive summary:
In a valid guideline study a degradation rate of 69 % was obtained after 28 days, thus the test substance Ethylene glycol dimethacrylate has to be classificated as readily biodegradable, but failing 10-day window.
NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Guideline study (EEC Dir. 84/449, published in: Official Journal of the European Communities, No. L251/188, Closed Bottle Test), GLP. 10-day-window not reached.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Dir. 84/449, published in: Official Journal of the European Communities, No. L251/188, Closed Bottle Test
- Principles of method if other than guideline:
- The biodegradation of organic compounds is determined by the determination of oxygen consumption of microorganisms using closed bottles filled with a mineral nutrient solution and the substance as the only carbon source.
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Test substance: Ethyleneglycol dimethacrylate EGDMA CAS: 97-90-5
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Samples of
microorganisms of a secondary effluent were withdrawn from a sewage plant mainly fed with domestic sewage. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2.01 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 71.2
- Sampling time:
- 28 d
- Remarks on result:
- other: 10-d window was not reached
- Parameter:
- % degradation (O2 consumption)
- Value:
- 29.3
- Sampling time:
- 5 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 31.2
- Sampling time:
- 10 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 41.1
- Sampling time:
- 15 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- In a valid guideline study a degradation rate of 71.2% was obtained after 28 days, thus the test substance Ethylene glycol dimethacrylate has to be classificated as readily biodegradable, but failing 10-day window.
- Executive summary:
According to the measured values of O2 -concentrations (in dependance of time, x) in the test vessels (with/without test
material/inoculum) via O2 -electrode, was calculated the BODx (Biological Oxygen Demand, in dependance of time, x). Via the BODx,
the ThOD and the concentration of the test substance EGDMA (Ethylene glycol dimethacrylate) in solution, the biotic Degradation at time x was calculated. The
calculation of Dt, the biodegradation rate in time, was performed according to the following formula: Dt(%) = [(mg BODx /l) : (mg
Subst / l x ThOD)] x 100 Description of the curve of biodegradation (%): After a lag phase of about 10 days biodegradation takes
place. Within the following 10 days, after 10% biodegradation was exceeded, about 40% degradation was obtained. Finally, a
degradation rate of 71.2% was obtained. Since degradation time (28 days), belonging to the degradation rate of about > 60%, exceeded
the 10 days window, Ethylene glycol dimethacrylate has to be classificated according to the criteria of test evaluation as readily biodegradable, but failing 10-day window.
Referenceopen allclose all
Oxygen contents and calculations of the degradation rate of the test substance and the reference substance
(table 1):
O2-Analysis was performed with an oxygen electrode; ThOD: 1.86 mg/mg subst.; Temp.of the dilution water after aeration: 20°C; O2-concentration of the water after aerartion and standing (20hours) before start: 8.61mg/l; stock solution of the test substance (Ethylene glycol dimethacrylate): 250 mg/l; stock solution of the reference substance (Aniline): 100 mg/l; Test procedure: 4 Groups of BOD bottles were prepared: 1 ) air-bubble free with the medium containing the test material (Test-Substance, TS) 2) air-bubble free with the medium containing the reference material (Ref-Substance, Rf)3) air-bubble free with the medium containing only microorganisms (Io-Bl) 4) air-bubble free with the mineral medium containing the oxygen blanc (O2-Contr). The oxygen was determined at the days 0, 5, 10, 15 and 28 elektochemically (see: table1) (oxygen probe: WTW EO 166; measuring instrument: WTWOXI 550). For the time in between the measurements the bottles were incubated at 20°C in the dark.. |
Description of key information
According to different test guidelines (Screening tests OECD 301 F and OECD 301 D) Ethyleneglycol dimethacrylate was assessed to be readily biodegradable in activated sludge (> 60 % degradation within 28 days) but failing the 10-day window. (Evonik Industries 2012 and 1990).
BIOWIN v4.10 prediction: readily biodegradable.
This is likely due to the kinetics of sequential metabolism since both primary metabolites, Hydroxyethyl methacrylate and methacrylic acid are readily biodegradable acc. OECD criteria. Consequently, it is expected that Ethyleneglycol dimethacrylate will be ultimately biodegraded within 28 days.
Conclusion:
Ethyleneglycol dimethacrylate is assessed to be readily biodegradable, but failing 10-day window. Utimate biogeradation is expected within 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
Hydroxyethyl methacrylate (CAS 868-77-9) and Methacrylic acid (CAS 79-41-4) are expected to be the primary metabolites of Ethyleneglycol dimethacrylate. Both substances are readily biodegradable acc. OECD criteria. Microbial metabolism simulator of OECD Toolbox version 3.3.0-132 generates in summary of both substances (HEMA and Methacrylic acid) similar metabolites as Ethyleneglycol dimethacrylate itself. This information supports the assumption that EGDMA will be biodegardable utimately wthin 28 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.