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reaction mass of: tetrasodium 4-amino-6-(5-(2,6-difluoropyrimidin-4-ylamino)-2-sulfonatophenylazo)-5-hydroxy-3-(4-(sulfatoethylsulfonyl)phenylazo)naphthalene-2,7-disulfonate;tetrasodium 4-amino-6-(5-(4,6-difluoropyrimidin-2-ylamino)-2-sulfonatophenylazo)-5-hydroxy-3-(4-(2-sulfatoethylsulfonyl)phenylazo)naphthalene-2,7-disulfonate
EC number: 431-830-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1998-03-03 to 1998-03-05
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 100 mg/L, and blank control
- Sampling method: No data
- Sample storage conditions before analysis: No data - Vehicle:
- no
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: No auxiliary agent was used.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna STRAUS, parthenogenetic females
- Source: cloned at the Federal Health Office (BGA) in Berlin, bred at Bayer AG Leverkusen
- Age at study initiation (mean and range, SD): 0-24 hours
- Weight at study initiation (mean and range, SD): No data
- Length at study initiation (length definition, mean, range and SD): No data
- Medium: In M4 medium according to Elendt and BGA (1992)
- Feeding during test: Not stated
ACCLIMATION
- Acclimation period: No data
- Acclimation conditions (same as test or not): Not stated
- Type and amount of food: Not stated
- Feeding frequency: Not stated
- Health during acclimation (any mortality observed): No data - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Post exposure observation period:
- None
- Hardness:
- 15 mg CaCO3/L
- Test temperature:
- 19.9-20 °C
- pH:
- 8.1
- Dissolved oxygen:
- 8.6-8.8 mg/L
- Salinity:
- Not measured
- Nominal and measured concentrations:
- Nominal: 100 and 0 mg/L (control)
Measured: 77 mg/L (based on TOC concentrations and molecular weight calculations) - Details on test conditions:
- TEST SYSTEM
- Test vessel: cylindrical test vessels (diameter 4.0 cm, height 6.5 cm), 20 ml test medium, not ventilated
- No. of organisms per vessel: 10
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: M4-Medium according to Elendt and BGA (1992)
TEST CONCENTRATIONS
- Nominal test concentrations: 100 mg/L
Assessment of effect: immobilisation of daphnia - Reference substance (positive control):
- no
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 77 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
- Details on results:
- % loss of test substance over test: >20%
Behavioural abnormalities: Not stated
The immobilisation rates of daphnids after 24 hours of exposure could not be determined because of intensive colour of the test medium. - Results with reference substance (positive control):
- Not applicable
- Reported statistics and error estimates:
- None
- Validity criteria fulfilled:
- yes
- Conclusions:
- No toxic effects of Reactive Navy FC63805 to female partheogenetic Daphnia magna were observed after 48 hours at a nominal 100 mg/L concentrations. Therefore the EC50 is > 77 mg/L (measured concentration) at 48 hours.
- Executive summary:
The 48-h acute toxicity of Reactive Navy FC63805 to Daphnia magna STRAUS, parthenogenetic females, was studied under static conditions. Daphnids were exposed to 100 mg/L of the test substance for 48 h. The 48-hr EC0 was > 77 mg/L (measured concentration).
This study is classified as acceptable and satisfies the guideline requirements for an acute toxicity study with freshwater invertebrates.
Results synopsis
Test organism age: 0–24 hours
Test type: Static
EC0: > 77 mg/L at 48 hours
Reference
Description of key information
No toxic effects of Reactive Navy FC63805 to female partheogenetic Daphnia magna were observed. Therefore the (hypothetical) EC0 would be > 77 mg/L at 48 hours.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Daphnia magna STRAUS, parthenogenetic females, were exposed to a limit test concentration of 100 mg/L test substance in water (nominal). The test substance concentration was analytically confirmed to be 77 mg/L at the end of the exposure. Observations were made on the mobility behaviour after 24 and 48 hours of exposure. No immobility occurred at any point in time during the test. Accordingly, the EC0 at 48 h was >77 mg/L (measured concentration). An EC50 cannot be determined.
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