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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to OECD and GLP guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report date:
2003

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, B.1
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
4-bromo-2,6-difluorobenzoic acid
EC Number:
457-940-3
EC Name:
4-bromo-2,6-difluorobenzoic acid
Cas Number:
183065-68-1
Molecular formula:
Hill formula: C7H3BrF2O2 CAS formula: C7H3BrF2O2
IUPAC Name:
4-bromo-2,6-difluorobenzoic acid

Test animals

Species:
other: rat, HsdCpb:WU

Administration / exposure

Vehicle:
other: Methocel K4M premium solution

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 3; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 3; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels:
Keine Toxizität

"ENGLISH"

No toxicity
Gross pathology:
Effects on organs:
Keine Effekte

"ENGLISH"

No effects

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

The acute oral toxicity of 4-Bromo-2,6-difluorobenzoic acid was tested according to OECD 423. The LD50 of 4-Bromo-2,6-difluorobenzoic acid is > 2000 mg/kg bw after oral treatment of rats.