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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
National Library of Medicine HSDB Database
Year:
2001
Bibliographic source:
Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 p.1002] **PEER REVIEWED**

Materials and methods

Principles of method if other than guideline:
Method not published
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloroaniline
EC Number:
203-581-0
EC Name:
3-chloroaniline
Cas Number:
108-42-9
Molecular formula:
C6H6ClN
IUPAC Name:
3-chloroaniline

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
500 - 800 other: mg/cu m/4 hr
Based on:
not specified
Exp. duration:
4 h

Any other information on results incl. tables

Lungs, thorax or respiration: cyanosis

Vehavioral: convulsions or effect on sezure threshold

Sense organs and special senses (eye): corneal damage

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information Criteria used for interpretation of results: EU