Registration Dossier
Registration Dossier
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EC number: 601-593-4 | CAS number: 119302-19-1
Endpoint summary
Administrative data
Description of key information
Additional information
The 48h-EC50 of Epyrron was 5.1 mg/l based on average exposure concentrations (95% confidence interval between 4.4 and 6.1 mg/l), and by read acros the 48h-EC50 of Epyrrol is considered to be similar.
Under the conditions of the present study withPseudokirchneriella subcapitata, Epyrron-OPL reduced growth rate and inhibited the yield of this fresh water algae species significantly at all of the concentrations tested.
By read across the EC50 for growth reductions and yield inhibitions for Epyrrol are considered similar.
The EC10for growth rate reduction (72h-ERC10) was 0.018 mg/l with a 95% confidence interval ranging from 0.0095 to 0.033 mg/l, based on TWA concentrations.
The EC50for growth rate reduction (72h-ERC50) was 1.4 mg/l with a 95% confidence interval ranging from 1.3 to 1.6 mg/l, based on TWA concentrations.
Detailed justification for the read-across approach is attached to this section.
Based on the experimental results described above, Epyrron meets the criteria for classification as Aquatic Chronic Cat 2, H411, according to EU CLP.
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