Registration Dossier
Registration Dossier
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EC number: 204-707-7 | CAS number: 124-64-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
THPS: acute immobilisation test on Daphnia magna (OECD Test Guideline 202, 48 h). The results: NOEC = 10.4 mg/L, LC50 = 19.4 mg/L (nominal concentrations in terms of test item).
THPS: acute test (48 h) brine shrimp Acartia tonsa. The result: LC50 = 0.6 mg/L in terms of test item.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 19.4 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 0.6 mg/L
Additional information
The read-across with THPS is considered to be allowed for THPC because the toxicity is triggered by the organic phosphonium cation which is the same for both substances. The influence of the anions (chloride and sulfate) regarding the toxicological behaviour is considered not to be relevant.
Physico chemical parameter (high water solubility, negative logPow) which influence the toxicological and environmental behavior are comparable in case of THPC and THPS.THPS was investigated in an acute immobilisation test according to OECD Test Guideline 202 for 48 hours on Daphnia magna. The results (nominal concentrations in terms of test item) were as follows: NOEC = 10.4 mg/L, LC50 = 19.4 mg/L.
THPS was investigated in an acute test (48 h) towards the marine brine shrimp Acartia tonsa. The result is as follows: LC50 = 0.6 mg/L in terms of test item.
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