Registration Dossier
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EC number: 227-047-1 | CAS number: 5619-04-5
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 June 2014-07 September 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-compliant study in accordance with EC A.5 and OECD 115.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.5 (Surface Tension)
- Version / remarks:
- (2008)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Version / remarks:
- (1995)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- OECD harmonised ring method
Test material
- Reference substance name:
- Methyl DL-serinate hydrochloride
- EC Number:
- 227-047-1
- EC Name:
- Methyl DL-serinate hydrochloride
- Cas Number:
- 5619-04-5
- Molecular formula:
- C4H9NO3.ClH
- IUPAC Name:
- methyl 2-amino-3-hydroxypropanoate hydrochloride
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): DL-serine Methylester HCl
- Molecular formula: C4H9NO3.HCl
- Molecular weight: 155.58 g/mol
- Description: White crystalline powder
- Storage condition of test material: At room temperature in the dark
- Expiration date of the lot/batch: 14 September 2014
Constituent 1
Results and discussion
Surface tension
- Surface tension:
- 76 mN/m
- Temp.:
- 20 °C
- Conc.:
- 1 g/L
Any other information on results incl. tables
Surface tension measurements
Measurement
|
Time passed [minutes] |
Surface tension [mN/m] |
||
individual |
Mean |
mean (1) |
||
|
|
|
|
|
1 |
15 |
73.8 |
|
|
2 |
16 |
73.6 |
73.8 |
76.0 |
3 |
17 |
73.9 |
|
|
4 |
18 |
74.0 |
|
|
5 |
19 |
73.9 |
|
|
(1) Multiplied by Fb followed by correction according to Harkins-Jordan.
Applicant's summary and conclusion
- Conclusions:
- In a GLP-compliant study in accordance with EC A.5 and OECD 115 using the OECD Harmonized ring method, the surface tension of an 1 g/L aqueous solution of the substance has been determined as 76.0 mN/m at 20°C. Because this is not < 60 mN/m, the substance is not surface active according to the EC A.5 guideline.
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