Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 237-358-4 | CAS number: 13762-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
IC50 (9h) = 185.7 mg cobalt molybdenum oxide/L (Tetrahymena pyriformis) for growth inhibition (read-across from cobalt chloride)
Key value for chemical safety assessment
- EC50 for microorganisms:
- 185.7 mg/L
Additional information
No data on toxicity to microorganisms are available for cobalt molybdenum oxide. However, there are reliable data available for different structurally analogue substances.
The environmental fate pathways and ecotoxicity effects assessments for cobalt metal and cobalt compounds as well as for molybdenum metal and molybdenum compounds is based on the observation that adverse effects to aquatic, soil- and sediment-dwelling organisms are a consequence of exposure to the bioavailable ion, released by the parent compound. The result of this assumption is that the ecotoxicology will be similar for all soluble cobalt and molybdenum substances used in the ecotoxicity tests. Therefore, data from soluble cobalt and molybdenum substances are used in the derivation of ecotoxicological and environmental fate endpoints, based on the cobalt ion and molybdenum ion, respectively.
Cobalt
Data on single-species toxicity tests resulting in high quality L(I)C50 values (expressed as Co) for microorganisms are summarised in the WHO CICAD, 2006 (see attached table).
In the key study, the effects of cobalt chloride on the protozoan Tetrahymena pyiformis in a 9 hour flask test were investigated (Sauvant et al., 1995). The IC50 (9h) for growth inhibition was 50 mg Co/L, resulting in a recalculated value of 185.7 mg cobalt molybdenum oxide/L.
Another study on the ciliate Spirostomum ambiguum showed a LC50 (24h) value of 11.8 mg Co/L using cobalt nitrate as salt, equivalent to a value of 43.8 mg cobalt molybdenum oxide/L (WHO CICAD, 2006).
References: World Health Organization (2006). Concise International Chemical Assessment Document 69.COBALT AND INORGANIC COBALT COMPOUNDS.
Molybdenum
Data on the toxicity tests performed with aquatic bacteria and protozoa, reported as EC50, EC10 and NOEC values are summarized below. It can be noted that there are insufficient useful data for aquatic micro-organisms to apply statistical extrapolation. From the extracted results, two test results were considered relevant for assessment purposes for micro-organisms in STPs: the activated sludge test with pure MoO3(HRC, 1994) and the activated sludge test with sodium molybdate (Stearns, 1985). As the second study resulted in the highest, unbounded NOEC (i.e. > 950 mg/L), the value taken from the HRC (1994) study is put forward.
The lowest reliable observed EC10-value for respiration (inhibition of respiration after a 3h incubation period) using activated sludge was 216.5 mg Mo/L (HRC, 1994d). The test was conducted with molybdenum trioxide (MoO3) as test substance.
Bacteria – accepted studies
|
|||||||||||||||
Domestic activated sludge population |
MoO3, technical |
activated sludge + artificial sewage |
3 hour |
EC50 |
Inhibition of respiration |
1926 |
Huntington Research Center, 1994c |
||||||||
Domestic activated sludge population |
MoO3pure |
activated sludge + artificial sewage |
3 hour |
EC50 EC10 |
Inhibition of respiration |
546 216.5 (169.1-277.3) |
Huntington Research Center, 1994d |
||||||||
Domestic activated sludge population |
Sodium molybdate |
activated sludge |
30 min |
NOEC |
Oxygen utilization BOD-removal |
> 950 |
Stearns, 1985 |
||||||||
Domestic activated sludge population |
Sodium molybdate |
activated sludge |
30 min |
NOEC |
Sludge dewatering |
> 950 |
Stearns, 1985 |
Conclusion
As
the effect values derived from analogue cobalt compounds are
considerably lower than those derived from analogue molybdenum
substances, it can be reasoned that the cobalt ion will account for the
effects in ecotoxicological testing. Hence, it was concluded to put
forward the most sensitive and reliable results derived from analogue
cobalt compounds for assessment purposes, and recalculate them for
CoMoO4.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.