Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-869-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 July, 2011
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Solid Recovered Fuel (Municipal Solid Waste and similar wastes, processed)
- EC Number:
- 700-869-2
- Molecular formula:
- Not applicable
- IUPAC Name:
- Solid Recovered Fuel (Municipal Solid Waste and similar wastes, processed)
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Crj: CD(SD)
- Sex:
- male/female
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- unchanged (no vehicle)
- Details on dermal exposure:
- Skin preparation:
24 hours before the beginning of the test the back and the sides of the animals have been shaved on an area of about 20 cm2.
Application:
The test sample has been given, a ratio of 2000 mg/kg, with a square of gauze directly on animals' skin humidified with sodium chloride injection and fixed with a skin patch in a area of about 10% of the total body surface.
the square has been put on the back of animals and further fixed with hypo-allergenic occlusive adhesive tape.
The whole trunk of the animal has been protected with an elastic bandage. Bandage has been left in situ for 24 hours, during this period animals have been kept in single cages.
Removal:
24 hours after application bandage and adhesive tape have been remove.
Skin has been cleaned from sample excess by a tampon soaked in physiological solution. - Duration of exposure:
- 24 hours
- Doses:
- The test sample has been given, a ratio of 2000 mg/kg, with a square of gauze directly on animals' skin humidified with sodium chloride injection and fixed with a skin patch in a area of about 10% of the total body surface.
- No. of animals per sex per dose:
- 10 (5 males and 5 females)
- Control animals:
- not specified
- Details on study design:
- Observations
The general status of all animals has been daily monitored after 1-3-5 hours from the start of treatment and daily (5 days per week) for 14 days.
All activies related to the study, as well as remarks and exams have been daily registered in dated and signed forms.
During the study the following observations have been done:
- Mortality
Animals have been observed in the morning of each working day (5 days/week).
- Clinical symptomatology
Every clinical symptom, including possible variations of somato-motory activity, was daily registered for each individual animal.
Clincial observations included a general objective exam (G.O.E.) above:
1.assessment of major organic functions;
2. assessment of the status of integumentary apparatus;
3. assessment of the status of mucosae;
4. assessment of somato-motory activity and of the sensory status.
- Body weight
Animals have been weighted before experiment, after 7 days and at the end of the experiment.
- Post mortem
At the end of the observation period, animals have been sacrificed and a post-mortem examination has been carried out.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- During the study no mortality was detected.
- Clinical signs:
- other: During the study neither symptoms nor signs of toxicity were recorded.
- Other findings:
- - Post mortem observations
At the autopsy no abnormalities have been detected.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test substance has a LD50 > 2000 mg/kg bw and can be considered NOT TOXIC - NOT HARMUFUL.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.