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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
24-10-2014 to 07-11-2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
no
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
-24.6 °C
Decomposition:
no
Sublimation:
no

For the two DSC measurements the test item was cooled down from ambient temperature to -100 °C with a cooling rate of 0.25 K/min. The samples were kept for 60 min at -100 °C and subsequently heated up to 50 °C at a constant heating rate of 10 K/min. Both DSC measurements in aluminium crucibles with a hole showed an endothermal effect in the temperature range of -40 to -10 °C with onset temperatures of - 24.25 °C and - 25.03 °C, respectively.

Table 1: Melting point (DSC measurements)

Ident No.

Test item mg

Final test temperature °C

Type of effects

Temperature range °C

Onset °C

Crucible

34700

19.48

50

endothermic

(-40) – (-10)

-24.25

Aluminium with a hole

34704

11.41

50

endothermic

(-35) – (-10)

-25.03

Aluminium with a hole

 

The test item appeared unchanged after the measurements. No mass loss occurred. From the results of the DSC measurements it was concluded that the test item had a melting point of -24.6 °C.

Conclusions:
The melting point of the test item was determined to be -24.6 °C at atmospheric conditions.
Executive summary:

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with 19 mg and 11 mg of the test item were performed. For the two DSC measurements the test item was cooled down from ambient temperature to -100 °C with a cooling rate of 0.25 K/min. The samples were kept for 60 min at -100 °C and subsequently heated up to 50 °C at a constant heating rate of 10 K/min. Both DSC measurements in aluminium crucibles with a hole showed an endothermal effect in the temperature range of -40 to -10 °C with onset temperatures of - 24.25 °C and - 25.03 °C, respectively. The test item appeared unchanged after the measurements. No mass loss occurred. From the results of the DSC measurements it was concluded that the test item had a melting point of -24.6 °C.

Description of key information

The melting point of the test item was determined to be -24.6 °C at atmospheric conditions.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-24.6 °C

Additional information

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed into an aluminium crucible under an inert atmosphere (nitrogen). Two tests with 19 mg and 11 mg of the test item were performed. For the two DSC measurements the test item was cooled down from ambient temperature to -100 °C with a cooling rate of 0.25 K/min. The samples were kept for 60 min at -100 °C and subsequently heated up to 50 °C at a constant heating rate of 10 K/min. Both DSC measurements in aluminium crucibles with a hole showed an endothermal effect in the temperature range of -40 to -10 °C with onset temperatures of - 24.25 °C and - 25.03 °C, respectively. The test item appeared unchanged after the measurements. No mass loss occurred. From the results of the DSC measurements it was concluded that the test item had a melting point of -24.6 °C (reference 4.2-1).