Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 412-180-1 | CAS number: 10221-57-5 1,2-DIETHOXYPROPANE; DIETHOXY-1,2-PROPANE
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
4.1. Description of first aid measures
First-aid measures general : Take off immediately all contaminated clothing. Place the victim in the recovery position.
First-aid measures after inhalation : Allow affected person to breathe fresh air. If experiencing respiratory symptoms: Call a
poison center or a doctor.
First-aid measures after skin contact : After contact with skin, take off immediately all contaminated clothing, and wash
immediately with plenty of water and soap. If skin irritation occurs: Get medical
advice/attention.
First-aid measures after eye contact : Rinse immediately with plenty of water. Remove contact lenses, if present and easy to do.
Continue rinsing. If eye irritation persists: Get medical advice/attention.
First-aid measures after ingestion : Rinse mouth. Never give anything by mouth to an unconscious person. Get medical
advice/attention.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms/effects after skin contact : Slightly irritating to the skin.
Symptoms/effects after eye contact : Slightly irritant to eyes.
4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.
Fire-fighting measures
5.1. Extinguishing media
Suitable extinguishing media : carbon dioxide (CO2), dry chemical powder, foam.
Unsuitable extinguishing media : Do not use a heavy water stream.
5.2. Special hazards arising from the substance or mixture
Fire hazard : Under fire conditions, hazardous fumes will be present.
Explosion hazard : Vapours may form explosive mixture with air. Heavier than air, vapours may travel long
distances along ground, ignite and flash back to source.
Hazardous decomposition products in case of fire : Carbon oxides (CO, CO2).
5.3. Advice for firefighters
Precautionary measures fire : Exercise caution when fighting any chemical fire. Do not breathe fumes from fires or
vapours from decomposition.
Firefighting instructions : Eliminate all ignition sources if safe to do so. Use water spray or fog for cooling exposed
containers. Contain the extinguishing fluids by bunding. Fight fire from safe distance and
protected location. Evacuate the danger area.
Protection during firefighting : Do not enter fire area without proper protective equipment, including respiratory protection.
Self-contained breathing apparatus. Wear fire/flame resistant/retardant clothing.
Other information : Large amounts of the product should not be allowed to enter drains or water courses or be
deposited where it can affect ground or surface waters.
Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures
General measures : Exclude sources of ignition and ventilate the area.
6.1.1. For non-emergency personnel
Emergency procedures : Mark out the contaminated area with signs and prevent access to unauthorized personnel.
Do not breathe vapours. Avoid contact with skin, eyes and clothing.
6.1.2. For emergency responders
Protective equipment : Equip cleanup crew with proper protection. Wear suitable protective clothing, gloves and
eye or face protection.
Emergency procedures : Ventilate area.
6.2. Environmental precautions
Dispose of this material and its container to hazardous or special waste collection point. Do not discharge into drains or the environment.
6.3. Methods and material for containment and cleaning up
For containment : Contain the spilled material by bunding. Soak up spills with inert solids, such as clay or
diatomaceous earth as soon as possible. Mechanically recover the product.
Methods for cleaning up : Wash away remainder with plenty of water.
Other information : Use closed containers for waste packaging and confinement. Dispose of contaminated
material at an authorized site.
6.4. Reference to other sections
See Heading 8. See Heading 13.
Handling and storage
7.1. Precautions for safe handling
Additional hazards when processed : Highly flammable liquid and vapour. Handle empty containers with care because residual
vapours are flammable. May form explosive peroxides.
Precautions for safe handling : Do not get in eyes, on skin, or on clothing. Avoid all unnecessary exposure. Do not breathe
vapours. Provide good ventilation in process area to prevent formation of vapour. Use
personal protective equipment as required. Keep away from heat, hot surfaces, sparks,
open flames and other ignition sources. No smoking. Prevent the build-up of electrostatic
charge. Proper grounding procedures to avoid static electricity should be followed.
Hygiene measures : Take off immediately all contaminated clothing. Do not eat, drink or smoke when using this
product. Wash hands and other exposed areas with mild soap and water before eating,
drinking or smoking and when leaving work. Handle in accordance with good industrial
hygiene and safety practice.
7.2. Conditions for safe storage, including any incompatibilities
Technical measures : Use special care to avoid static electric charges. Ground well. Provide local exhaust or
general room ventilation to minimize vapour concentrations.
Storage conditions : Keep in a cool, well-ventilated place away from moisture. Store in tightly closed containers.
Keep container closed when not in use. Keep away from heat, hot surfaces, sparks, open
flames and other ignition sources. No smoking. Avoid the build-up of electrostatic charge.
Incompatible materials : Strong oxidizing agents.
Storage temperature : < 25 °C
Heat and ignition sources : Keep away from open flames, hot surfaces and sources of ignition.
Special rules on packaging : Keep container tightly closed.
7.3. Specific end use(s)
No additional information available
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
8.1. Control parameters
No additional information available
8.2. Exposure controls
Personal protective equipment:
Safety glasses. Gloves. Use protective clothing. Protective clothing.
Hand protection:
Nitrile rubber gloves
Eye protection:
Wear tight fitting safety glasses or facial screen
Skin and body protection:
In case of repeated or prolonged exposure : Fully enclosed impervious protective suit with integral or tight-fitting gloves, boots, self-contained or
supplied air respirator must be worn
Respiratory protection:
Provide good ventilation in process area to prevent formation of vapour. In case of insufficient ventilation, wear suitable respiratory equipment.
Gas mask with filter type A2B2
Personal protective equipment symbol(s):
Other information:
Emergency safety showers should be available in the immediate vicinity of any potential exposure.
Stability and reactivity
10.1. Reactivity
Highly flammable liquid and vapour.
10.2. Chemical stability
Stable under normal conditions of use.
10.3. Possibility of hazardous reactions
The substance can form explosive peroxides. Highly flammable liquid and vapour. The vapours are denser than air and may travel along the
ground. Distance ignition possible.
10.4. Conditions to avoid
Avoid ignition sources. Keep away from heat and direct sunlight.
10.5. Incompatible materials
Strong oxidizing agents.
10.6. Hazardous decomposition products
Under normal conditions of storage and use, hazardous decomposition products should not be produced.
Disposal considerations
13.1. Waste treatment methods
Regional legislation (waste) : Disposal must be done according to official regulations.
Waste treatment methods : Dispose of this material and its container at hazardous or special waste collection point. Do
not empty into drains.
Sewage disposal recommendations : Do not flush down sewers.
Product/Packaging disposal recommendations : Completely empty the packaging prior to decontamination. Beware of residues or vapours
which remain in the drums.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.