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Diss Factsheets
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EC number: 609-203-4 | CAS number: 36130-02-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Dec 2015 to 06 Apr 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
- Deviations:
- no
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Key result
- Test procedure:
- burning rate test: preliminary screening test
- Remarks on result:
- substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period
- Interpretation of results:
- not classified based on GHS criteria
- Conclusions:
- Fluocortolon-21-valerat is in the sense of the CLP-Directive a not flammable solid.
- Executive summary:
Fluocortolon-21 -valerat is classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1. Fluocortolon-21 -valerat is in the sense of the CLP-Directive a not flammable solid. The test was performed as stipulated in UN test procedure ‘Recommendations on the Transport of Dangerous Goods-Manual of Tests and Criteria’ (UN-MTC), Part III, sub-section 33.2.1.4.1, Test N.1 ‘Test method for readily combustible solids’.
- Endpoint:
- self-heating substances / mixtures
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09 Feb to 25 May 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- according to guideline
- Guideline:
- other: German standard method "VDI 2263, Part 1 ‘Test Methods for the Determination of the Safety Characteristic of Dusts’"
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Test procedure:
- other: Grewer oven test
- Result:
- negative outcome (no effect observed)
- Interpretation of results:
- not classified based on GHS criteria
- Conclusions:
- Fluocortolon-21-Valerat is not a self-heating substance in the sense of CLP Annex I, 2.11.
- Executive summary:
Appendix 6, point 5.2.2 of UN-MTC test procedure refers to the Grewer oven test. The test was performed as stipulated in test procedure VDI 2263, Part 1 ‘Test Methods for the Determination of the Safety Characteristic of Dusts’.
The sample in its delivery state and an inert reference sample are heated up to 410 °C at a rate of 0.5 K/min in an air flow of about 20 L/h.
No exothermic effects were determined up to the point at which the test substance melted. The wire mesh basket was empty after the measurement.
‘Fluocortolon-21-Valerat, ger.' is not a self-heating substance in the sense of CLP Annex I, 2.11. The determination according to UN-MTC Procedure N.4 (Bowes-Cameron-Cage-Test) is not necessary.
Referenceopen allclose all
The substance in its delivery state was measured. The test substance melted when approached by the ignition flame. The substance did not burn up. No further testing was required.
Validity criteria for the measurement of the flammability:
Target condition according to guideline 92/69/EWG A. 12: | Actual condition according to the study: | Validity criteria met: |
The report shall include the results of the tests (steps 1, 2, 3 and 4) and the chemical identity of gas evolved. | The results of the steps are stated. No gas evolution occured. | Yes |
The rate of evolution of gas if step 4 is performed shall be stated. | No gas evolution occured. | Yes |
The wire mesh basket was empty after the measurement.
Description of key information
a) Flammability: Fluocortolon-21-valerat is classified as a not readily combustible solid according to UN-MTC Procedure N.1.
b) Self-heating substances: Fluocortolon-21-valerat is not a self-heating substance in the sense of CLP Annex I, 2.11.
c) Pyrophoric properties: Fluocortolon-21-valerat did not deliver indications of pyrophoric properties during the realization of other tests. The determination according to UN-MTC Procedure N.2 is not necessary.
d) Contact with water: A review of the structure suggests that there are no chemical groups present that would imply pyrophoric properties or flammability on contact with water. A review of handling and use implies no pyrophoric properties or flammability on contact with water. Testing according to UN Procedure N.5 is not necessary.
Key value for chemical safety assessment
- Flammability:
- not classified
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.