5-(hydroxymethyl)-2-furaldehyde

Oxidising properties

Administrative data

Endpoint:

oxidising solids

Study period:

15 May 2019

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)

Version / remarks:

Recommendations on the TRANSPORT OF DANGEROUS GOODS: Manual of Tests and Criteria, 6th edition, New York and Geneva, 2015

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Reference substance 001

Cas Number:

67-47-0

Molecular formula:

C6H6O3

impurity 1

Reference substance name:

Fructose

EC Number:

200-333-3

EC Name:

Fructose

Cas Number:

57-48-7

Molecular formula:

C6H12O6

IUPAC Name:

D-fructose

impurity 2

Reference substance name:

1-(furan-2-yl)-2-hydroxyethanone

Cas Number:

17678-19-2

Molecular formula:

C6H6O3

IUPAC Name:

1-(furan-2-yl)-2-hydroxyethanone

impurity 3

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

water

impurity 4

Reference substance name:

Sodium formate

EC Number:

205-488-0

EC Name:

Sodium formate

Cas Number:

141-53-7

Molecular formula:

CH2O2.Na

IUPAC Name:

sodium formate

impurity 5

Reference substance name:

Sodium nitrate

EC Number:

231-554-3

EC Name:

Sodium nitrate

Cas Number:

7631-99-4

Molecular formula:

HNO3.Na

IUPAC Name:

sodium nitrate

impurity 6

Reference substance name:

Glucose

EC Number:

200-075-1

EC Name:

Glucose

Cas Number:

50-99-7

Molecular formula:

C6H12O6

IUPAC Name:

D-glucose

impurity 7

Reference substance name:

Sodium acetate

EC Number:

204-823-8

EC Name:

Sodium acetate

Cas Number:

127-09-3

Molecular formula:

C2H4O2.Na

IUPAC Name:

sodium acetate

impurity 8

Reference substance name:

2-furaldehyde

EC Number:

202-627-7

EC Name:

2-furaldehyde

Cas Number:

98-01-1

Molecular formula:

C5H4O2

IUPAC Name:

2-furaldehyde

impurity 9

Reference substance name:

Sodium 4-oxovalerate

EC Number:

243-378-4

EC Name:

Sodium 4-oxovalerate

Cas Number:

19856-23-6

Molecular formula:

C5H8O3.Na

IUPAC Name:

sodium 4-oxopentanoate

impurity 10

Reference substance name:

Formaldehyde

EC Number:

200-001-8

EC Name:

Formaldehyde

Cas Number:

50-00-0

Molecular formula:

CH2O

IUPAC Name:

formaldehyde

Test material form:

solid: crystalline

Details on test material:

freeze-dried material
Batch: 1808A-RO-C-I1-FD-Chg#3
Appearance Crystal / brown
Storage: Refrigerator (2 - 8 °C)
Expiring date: 31 December 2019

Specific details on test material used for the study:

Storage Conditions: Dry, dark and cooled (2 °C to 8 °C)
Expiry Date: 2019-12-31

Results and discussion

Test results (Oxidising solids)

Key result

Remarks on result:

other: Based on the chemical composition of the product and the chemical structure of the single components present in the test item, it is concluded that the test item has no oxidizing properties.

Any other information on results incl. tables

The main components 5-(Hydroxymethyl)furfural (CAS no. 67-47-0), Fructose (CAS no.  57-48-7), 1-(furan-2-yl)-2-hydroxyethan-1-one (CAS no. 17678-19-2), Glucose (CAS no.  50-99-7) and Sodium formate (CAS no. 141-53-7) contain oxygen chemically only bonded to carbon or hydrogen. For these components oxidizing properties can be excluded. 

The test item also contains a small amount Sodium nitrate (CAS no. 7631 -99 -4), which is classified as oxidizing solid in Division 5.1 (Packing Group III) according to UN Recommendations on the TRANSPORT OF DANGEROUS GOODS: Model Regulations Volume I, Rev. 20, New York and Geneva, 2017. Since all other main components do not have oxidizing properties, it can be stated that the small amount of Sodium nitrate will not have an effect on the oxidizing potential of the whole product. The same applies to the other components with a mass fraction below 1 % w/w.

In addition, the test item contains no other components except for water, which is known to have no oxidizing properties.

Based on the fulfillment of the above cited requirements of Appendix 6 for the main components, it can be stated that the test item 5-(Hydroxymethyl)furfural has no oxidizing properties.

Applicant's summary and conclusion

Interpretation of results:

GHS criteria not met

Conclusions:

Based on the chemical composition of the product and the chemical structure of the single components present in the test item, it is concluded that 5-(Hydroxymethyl)furfural has no oxidizing properties.
Based on the chemical structures, the test item should not be classified by:
UN Transport Regulation: The test item does not have to be classified as oxidizing solid in Division 5.1 according to the UN Transport Regulation.
GHS and EC 1272/2008 (CLP Regulation), Annex 1: 2.14: The test item does not have to be classified as oxidizing solid according to GHS and EC 1272/2008 (CLP Regulation) Annex 1: 2.14.

Executive summary:

Based on the chemical composition of the product and the chemical structure of the single components present in the test item, it is concluded that 5-(Hydroxymethyl)furfural has no oxidizing properties.  

Based on the chemical structures, the test item should not be classified by:

UN Transport Regulation: The test item does not have to be classified as oxidizing solid in Division 5.1 according to the UN Transport Regulation.

GHS and EC 1272/2008 (CLP Regulation), Annex 1: 2.14: The test item does not have to be classified as oxidizing solid according to GHS and EC 1272/2008 (CLP Regulation) Annex 1: 2.14.