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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of the present study with Raphidocelis subcapitata, no statistically significant inhibition of growth rate was recorded at any of the concentrations of Pergafast 425 tested. The 72h-EC10, EC20 and EC50 values for inhibition of growth rate (ERCx) were beyond the range of concentrations tested, i.e. exceeded a time weighted average concentration of 50 µg/L.
Key value for chemical safety assessment
Additional information
An 72 hour toxicity study with freshwater algae (Pseudokirchneriella subcapitata) was conducted according to OECD guideline 201 and GLP prnciples. In addition, procedures were based on the test methods described in the OECD series on testing and assessment number 23. Algae were exposed to solutions containing 10, 18, 32, 56 and 100% of the SS, prepared at a loading rate of 100 mg/L. Samples taken from test solutions containing 32 and 100% of the SS were analysed. The measured concentrations were 18 and 58 µg/L at the start of the test, respectively. After 24 hours of exposure, the concentrations were at 91 and 98% of the initially measured values. The concentrations decreased during the last 48 hours of exposure, i.e. were at 45 and 66% relative to initial at the end of the test. The TWA concentration in the SS was calculated to be 50 µg/L. No significant differences were recorded between the values for growth rate at any of the test concentrations when compared to the control group. The 72h-EC10, EC20 and EC50 values for inhibition of growth rate (ERCx) were beyond the range of concentrations tested, i.e. exceeded a time weighted average concentration of 50 µg/L. The 72h-NOEC for growth rate was 50 µg/L, being considered as the maximum solubility of the test item in test medium. The study met the acceptability criteria, and is considered to be valid.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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