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EC number: 951-974-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
For MDEA-Esterquat C18 satd. a BCF of the same order of magnitude as the BCF of the structurally related source substance DODMAC (13 L/kg) is expected.
Key value for chemical safety assessment
- BCF (aquatic species):
- 13 L/kg ww
Additional information
Although not required under REACH Annex VIII following information about bioaccumulation aquatic/sediment will be given:
No experimental data for MDEA-Esterquat C18 satd. are available. Measured BCF data are available for Dimethyldioctadecyl ammonium chloride (DODMAC, CAS-No. 107-64 -2). DODMAC has a chemical structure similar to the target substance and is the molecular moiety of the target substance (MDEA-Esterquat C18 satd. ) for which the highest bioaccumulation potential is to be expected (1). MDEA Esterquat C18 satd. differs from DODMAC by the ester linking groups between the alkyl chains (of C18 chain length) and the headgroup (effectively the dimethyl ammonium group).
Regarding the BCF of the MDEA Esterquat C18 satd., the BCF is expected to be lower than that of DODMAC:
The chemical structure of the MDEA-Esterquat C18 satd. includes, in contrast to DODMAC, two polar ester moieties that lower BCF and which are susceptible to biodegradation and/or hydrolysis which also will result in a lower BCF of the MDEA Esterquat C18 satd. DODMAC is poorly biodegradable and much more stable than MDEA Esterquat C18 satd. For DODMAC no abiotic degradation is to be expected, for biotic degradation in water the degradation rate is very low (1.4 x 10E-4/d) (EU RAR, 2009).
Juvenile fish (Pimephales promelas) were exposed to DODMAC for 24 h under flow-through conditions, followed by a depuration period of 72 h. Without Humic acid, a BCF of 103.8 L/kg could be calculated based on the uptake rate constant (k1) of 1.35 mg/g x h and the depuration rate constant (k2) of 0.013 mg/g x h. With the addition of 1 mg/L and 6.8 mg/L Humic acid, the BCF was 37.5 and 2.8 L/kg, respectively (Versteeg & Shorter, 1992).
Based on naturally occurring concentrations of dissolved organic carbon (DOC) in the range of 2 to 10 mg/L in rivers and lakes, and 50% of the DOC being fulvic and humic acids (Thurman, 1985), the BCF obtained with the addition of 1 mg/L Humic acid can be considered to be most relevant.
The measured BCF values for similar substances (DODMAC, DHTDMAC(2)) are 12-32 (BUA Report 191, 1997) and 13-256 (EU RAR, 2002). The conclusion for DODMAC was “bioaccumulation is indicated, but it is assumed that it is low under environmental conditions. A BCF of 13 L/kg is used in the risk assessment…” (EU RAR, 2009).
The calculated BCF value for MDEA Esterquat C18 satd. is 70.8 L/kg (BCFBAF v3.01; CFCS 2015).
The low bioavailability of the substance (due to rapid and strong sorption to negatively charged surfaces in the aquatic environment) in combination with the rapid (bio)degradation of the bioavailable fraction (mainly due to the hydrolysis of the ester bond), make high bioconcentration factors for the substance even more improbable (Comber et al., 2003 in Hera, 2008).
For MDEA Esterquat C18 satd. a BCF of the same order of magnitude as the BCF of DODMAC (13 L/kg) is expected. The above information is considered as sufficient to support to the conclusion that the bioaccumulation potential of the registration substance is expected to be low (3).
(1) for a fatty acid derivative like the registration substance, bioaccumulation potential increases with increasing chain length of the fatty acid (within certain limits). Compound I has the longest fatty acid chain length among the molecules forming the registration substance.
(2) DHTDMAC: Dihydrogenated Tallow Alkyl Dimethyl Ammonium Chloride
(3) REACH Regulation, Annex XIII: a substance fulfils the bioaccumulation criterion when the bioconcentration factor (BCF) is higher than 2000
References:
EU, 2009: European Union Summary Risk Assessment Report - dimethyldioctadecylammonium chloride (DODMAC) - with addendum, available online: http://publications.jrc.ec.europa.eu/repository/handle/111111111/5276
HERA, 2008:Esterquats Environmental Risk Assessment Report, available online: http://www.heraproject.com/files/17-E-01-03-2008%20%20HERA%20EQ%20Environment%20Final%20Draft.pdf
191 BUA-Report: Dioctadecyl Dimethyl Ammonium Chloride (DODMAC) CAS-No. 107-64-2, Dihydrogenated Tallow Alkyl Dimethyl Ammonium Chloride (DHTDMAC) CAS-No. 61789-80-8,1. Dezember 1997
Comber MH,de Wolf W, Cavalli L, van Egmond R, Steber J, Tattersfield L, Priston RA. Assessment of bioconcentration and secondary poisoning of surfactants. Chemosphere. 2003 Jul;52(1):23-32
Thurman EM, Organic Geochemistry of Natural Waters. 1985, Springer
Versteeg DJ & Shorter JS. Effect of organic carbon on the uptake and toxicity of quaternary ammonium compounds to the fathead minnow, Pimephales promelas. Environmental Toxicology and Chemistry. 1992 Apr;11(4):571 -580
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