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EC number: 847-991-3 | CAS number: 90278-32-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Nov 09, 2015 - Jan 26, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- OECD 301F protocol
HJ/T 155-2004 the Guideline ofGood Laboratory Praetices on Chemical Testing, MEP, China - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- July 17, 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Version / remarks:
- EEC Publication No. L 383 A, December 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- The Guidelines of Good Laboratory Practices on Chemical Testing (HJ/T 155-2004, MEP, China).
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- The fresh activated sludge used in the test was collected from Wuzhong district urban area
sewage treatment plant. The address of the plant is No. 1, Baodai East Road, Suzhou city. The batch
No. ofinoculum was AS-20151103-01.
The activated sludge was washed with test medium after removing the suspended solids and
coarse particles on the day of collection, the activated sludge was centrifuged at 1100 g for 5 minutes,
and the supernatant was discarded. The process was repeated for 3 times.
The dry weight content of the activated sludge was determined in triplicates after pre-treatment,
and the average value was 10.63%. 75.2453 g of the activated sludge (wet weight) was weighed and
suspended it with test medium to made up to 2 litres (the dry weight concentration was calculated tobe
4 g/L based on the dry weight content of 10.63%). After that, the suspension was aerated for 6 days at
test temperature. The d1y weight content of the activated sludge was redetermined before inoculation
and the average value oftriplicate measurements was 5.69%. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 32 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1.68
- Sampling time:
- 14 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4.27
- Sampling time:
- 28 d
- Details on results:
- The percentage biodegradation oftest substance in duplicates were 2.52% and 0.84% (mean 1.68%) on day 14, and 7.63% and 0.90% (mean 4.27%) at the end of the test (on Day 28).
- Results with reference substance:
- The percentage biodegradation were 81.52% in procedure control on day 14, and 40.47% in the toxicity control on day 14, indicating that the inoculum was not inhibited by the test substance and met the test requirement.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The degradation rate of the test item did not reach 60 % within the 10-day window and after 28 days of incubation. Thus, the test item is not readily biodegradable.
- Executive summary:
The purpose of this study was to determine the ready biodegradability of the test item.
The information for this endpoint study record was obtained from an experimental study. The methods applied are fully compliant with OECD TG 301F.
The test item was exposed to aerobic activated sludge from the aeration tank of a domestic waste water treatment plant for 28 days. The biodegradation was followed by the oxygen uptake of the microorganisms during exposure. As a reference item sodium benzoate was tested simultaneously under the same conditions as the test item, and functioned as a procedure control. This type of study is recognized by the international test guidelines and should provide a rational basis to assess the ready biodegradation properties of the
test item when incubated with aerobic activated sludge.
The percentage biodegradation of the test substance in duplicates were 2.52% and 0.84% (mean 1.68%) on day 14, and 7.63% and 0.90% (mean 4.27%) at the end of the test on day 28. The percentage biodegradation were 81.52% in procedure control on day 14, and 40.47% in the toxicity control on day 14, indicating that the inoculum was not inhibited by the test substance and met the test requirement.
Under the conditions of this study the test item is considered to be not readily biodegradable.
Reference
Description of key information
OECD 301F: not readily biodegradable
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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