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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

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Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Literature data taken from the Hazardous Substances Data Bank
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data taken from the Hazardous Substances Data Bank
GLP compliance:
no
Dissociating properties:
yes
No.:
#1
pKa:
10.6
Temp.:
25 °C
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Value reported on Hazardous Substances Data Bank
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data reported in Hazardous Substances Data Bank
GLP compliance:
no
Dissociating properties:
no
pKa:
10.41
Temp.:
25 °C
pKa:
10.3
Remarks on result:
other: Temperature not reported

The study that the pKa value of 10.3 was reported in did not report the temperature at which the test was carried out.

Conclusions:
The substances is unlikely to possess dissociating properties.

Description of key information

pka (2,4 xylenol): 10.6

pka (2,5 xylenol): 10.4

Key value for chemical safety assessment

pKa at 20°C:
10.4

Additional information