Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-08-23 to 2018-09-12
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- July 27, 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- March 04, 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Version / remarks:
- August 1996
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Key result
- Atm. press.:
- 1 013 hPa
- Decomposition:
- yes
- Remarks:
- decomposition before boiling
- Decomp. temp.:
- >= 100 °C
- Remarks on result:
- not determinable
- Remarks:
- due to decomposition before boiling
- Conclusions:
- Reaction and/or decomposition before boiling (OECD 203): endothermic decomposition at >= 100°C
- Executive summary:
In a reliable study performed according to relevant guidelines (e.g. OECD 103) and compliant with GLP, the boiling point of the submission substance was to be determined. From differential scanning calorimetry (DSC) between 25 °C and 250 °C, an endothermic reaction peak became obvious:
Starting around 100°C, a pronounced endothermic effect was observed with a maximum at ca. 162 °C and a return to baseline at ca. 224 °C. Heating was continued up to 250 °C. After the experiment, a black molten residue remained in the sample container (original colour: red). The change of the colour indicated reaction and/or decomposition of the test item.
This result is in very good agreement with the DSC run performed earlier for determining the melting/freezing point (cooling phase between 25°C and -90°C with subsequent heating phase till 162 °C). Also in that run an endothermic effect was observed starting at 100°C with the peak not yet reached up to ca. 156 °C, which was the maximum temperature plotted for this DSC.
In conclusion, endothermic reaction and/or decomposition of the test item was observed during DSC experiments at temperatures of > 100°C (> 373K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.
Reference
Preliminary test (termogravimetric analyzer, TGA):
The TGA plot of the submission substance is given in the attached figure. Starting at 125°C, the weight of the sample decreased significantly. At 162°C, the sample weight had decreased by 25%. After the experiment, a black molten residue remained in the sample container (original colour: red). The change of the colour indicated reaction and/or decomposition of the test item.
Main Study (DSC):
In the experiment performed for determining the melting/freezing point (see IUCLID section 4.2 for details and plot of DSC run) during heating an endothermic effect was observed starting at 100°C. The endothermic effect was probably obtained due to reaction and/or decomposition of the test item (DSC was stopped at 162°C in this experiment). After the experiment, the residue remained unchanged based on visual observation.
To investigate the boiling point and to study the endothermic effect described above in more detail, the actual DSC experiment for determination of the boiling point was performed (see DSC plot in attached figure). Starting around 100°C, a pronounced endothermic effect was observed with a maximum at ca. 162 °C and a return to baseline at ca. 224 °C. Heating was continued up to to 250 °C After the experiment, a black molten residue remained in the sample container (original colour: red). The change of the colour indicated reaction and/or decomposition of the test item.
Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started.
Description of key information
Reaction and/or decomposition before boiling (OECD 203): endothermic decomposition at >= 100°C
Key value for chemical safety assessment
Additional information
In a reliable study performed according to relevant guidelines (e.g. OECD 103) and compliant with GLP, the boiling point of the submission substance was to be determined. From differential scanning calorimetry (DSC) between 25 °C and 250 °C, an endothermic reaction peak became obvious:
Starting around 100°C, a pronounced endothermic effect was observed with a maximum at ca. 162 °C and a return to baseline at ca. 224 °C. Heating was continued up to 250 °C. After the experiment, a black molten residue remained in the sample container (original colour: red). The change of the colour indicated reaction and/or decomposition of the test item.
This result is in very good agreement with the DSC run performed earlier for determining the melting/freezing point (cooling phase between 25°C and -90°C with subsequent heating phase up to 162 °C). Also in that run an endothermic effect was observed starting at 100°C with the peak not yet reached up to ca. 156 °C, which was the maximum temperature plotted for this DSC.
In conclusion, endothermic reaction and/or decomposition of the test item was observed during DSC experiments at temperatures of > 100°C (> 373K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.