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Diss Factsheets
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EC number: 701-290-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Two OECD 301B studies have been conducted on this substance. One of the guideline studies utilized pre-adapted inoculum following the guidelines for enhanced studies for the purposes of PBT assessment.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
Sucrose acetate isobutyrate has a very low water solubility and is therefore a difficult substance to test for a number of environmental endpoints including ready biodegradation. An initial study was performed to assess the ready biodegradability of the test item in an aerobic aqueous medium following the OECD 301B, Ready Biodegradability; C02 Evolution Test. Due to the low water solubility of the test substance, the test item was adsorbed onto granular silica gel prior to dispersion in the test medium to aid dispersion of the test item in the test medium and to increase the surface area of the test item exposed to the test organisms. In this study the test item attained 48% degradation after 28 days and therefore cannot be considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No 301 B.
A second study was performed to determine the potential for ultimate biodegradation of sucrose acetate isobutyrate in water by the carbon dioxide evolution method following OECD Test Guideline 301B using the enhanced technique of a low-level pre-adapted system similar to what is described in Chapter R.7B of the REACH guidance regarding enhanced ready biodegradation studies. A half and half mixture of inoculum from an initial ready biodegradation study (adapted) was combined with fresh un-adapted inoculum to initiate this study. All other aspects of the study met the criteria of the OECD 301B guideline method. In this study the test item attained 63.06% degradation after 28 days. The result showing greater than 60% ultimate biodegradation (CO2 evolution) in the 28 day test demonstrates a lack of persistence in a PBT assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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