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EC number: 419-240-6 | CAS number: 171054-89-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22.05.1995 - 30.05.1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- > 59.7 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 20 °C
- pH:
- 6.3
- Details on results:
- Result: Concentration of benzenebutanoic acid, 4-methyl-γ-oxo in a saturated solution of the test material = 36.2 g/l.
Result: Concentration of 4-ethylmorpholine in a saturated solution of the test material = >23.5 g/l.
Overall Result: Total concentration of benzenebutanoic acid, 4-methyl-γ-oxo and 4-ethlymorpholine in a saturated solution of the test material = >59.7 g/l. - Conclusions:
- In a saturated solution of the test material, the total benzenebutanoic acid, 4-methyl-γ-oxo and 4-ethlymorpholine in solution has been determined to be greater than 59.7 g/l at 20.0 +/- 0.5 °C.
- Executive summary:
A limit value is quoted for the concentration of 4-ethylmorpholine in a saturated solution of the test material as it is clear from the results generated that virtually all of this component had dissolved. Although preparing the sample solutions with a higher ratio of test material to water would have ensured the presence of excess 4-ethylmorpholine, the considerable excess of benzenebutanoic acid, 4-methyl-γ-oxo also present would have rendered the sample solutions unfilterable.
The concentration of benzenebutanoic acid, 4-methyl-γ-oxo and 4-ethylmorpholine in the standard solutions was calculated using the following data acquired in the Accelerated Storage Stability study, Safepharm project number 798/016.
The peak heights or areas of the pair of standards associated with a particular sample were corrected to nominal concentration and the mean value taken prior to the calculation of the sample concentration.
The experimental procedure used complies with that specified in Method A6 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
Reference
Description of key information
In a saturated solution of the test material, the total benzenebutanoic acid, 4-methyl-γ-oxo and 4-ethlymorpholine in solution has been determined to be greater than 59.7 g/l at 20.0 +/- 0.5 °C.
Key value for chemical safety assessment
- Water solubility:
- 59.7 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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