Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 256-277-5 | CAS number: 46729-07-1
Endpoint summary
Administrative data
Description of key information
Three acute aquatic studies are available for three trophic levels.
The 96h-LC50 for 4 -tert-butylcyclohexyl methacrylate is considered to be 590 mg/L (based on cyclohexyl methacrylate, 101-43-9 (read across substance)).
This result is confirmed with a non-GLP OECD 236 study, which showed that the 96h-EL50 > 100 mg/L for Danio rerio.
A study according to OECD guideline 202 under GLP, was performed to assess the effect of the test item.
Daphnia magna was exposed to solutions of the test item at nominal concentrations of 10, 18, 32, 56 and 100% v/v saturated solution for 48 hours. The geometric mean measured test concentration was determined to be 1.3 mg/L for 100% v/v saturated solution.
The 48h-EC50 > 1.3 mg/L (geomean), which is equal to the 100% v/v saturated solution.
A study according to OECD guideline 201 under GLP, was performed to assess the effect of the test item on the growth of the green alga Pseudokirchneriella subcapitata.
The 72h-ErC10 = 1.03 mg/L (geomean) and the 72h-ErC50 > 1.2 mg/L (geomean), which is equal to the 100% v/v saturated solution.
No acute effects were found up to the maximum water solubility; all acute endpoints are greater than the maximum water solubility of the test substance, therefore.
The toxicity of 4-(1,1-dimethylethyl)cyclohexyl methacrylate to activated sludge was determined in an OECD 209 study performed under GLP, at a contact time of 3 hours, using various concentrations of the test substance.
The 3h-EC50of the substance is >1280 mg/L, the highest concentration tested. The 3h-EC10 is 850 mg/L. 4-(1,1-dimethylethyl)cyclohexyl methacrylate is therefore considered not harmful to activated sludge.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
