Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 237-655-9 | CAS number: 13887-98-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2017-12-13 to 2018-01-17
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- see 'Principles of method if other than guideline'
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- see 'Principles of method if other than guideline'
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- yes
- Remarks:
- see 'Principles of method if other than guideline'
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: miscibility test with visual inspection
- Key result
- Temp.:
- 20 °C
- pH:
- >= 0.93 - <= 1.71
- Remarks on result:
- completely miscible
- Conclusions:
- In conclusion, the test item is miscible with water at ambient temperature.
- Executive summary:
The water solubility was determined according to OECD 105, Regulation (EC) No. 440/2008 method A.6 and OPPTS 830.7840. In a preliminary test no saturated solution of the test item could be prepared, therefore, the standard methods for determination of the water solubility are technically not feasible. Therefore, the water solubility of the test item was determined using the miscibility test with visual detection. The test item was mixed with ultrapure water in rations 1 :1, 1 : 9 and 9 : 1. After sonication and vigorous shaking the solubility was visually detected. The pH of each sample was recorded. The test substance was determined to be completely miscible in water at ambient temperature (pH 0.93 - 1.71).
Reference
Table 1. Water miscibility test
Test Item, (g) |
Water, (g) |
Observation |
pH value |
0.53 |
4.60 |
clear, homogeneous single-phase liquid |
1.71 |
0.52 |
4.54 |
clear, homogeneous single-phase liquid |
1.69 |
2.52 |
2.54 |
clear, homogeneous single-phase liquid |
1.42 |
2.51 |
2.55 |
clear, homogeneous single-phase liquid |
1.40 |
4.49 |
0.52 |
clear, homogeneous single-phase liquid |
0.93 |
4.50 |
0.51 |
clear, homogeneous single-phase liquid |
0.93 |
Description of key information
The test item is completely miscible in water at ambient temperature.
Key value for chemical safety assessment
Additional information
The water solubility was determined according to OECD 105, Regulation (EC) No. 440/2008 method A.6 and OPPTS 830.7840. In a preliminary test no saturated solution of the test item could be prepared, therefore, the standard methods for determination of the water solubility are technically not feasible. Therefore, the water solubility of the test item was determined using the miscibility test with visual detection. The test item was mixed with ultrapure water in rations 1 :1, 1 : 9 and 9 : 1. After sonication and vigorous shaking the solubility was visually detected. The pH of each sample was recorded. The test substance was determined to be completely miscible in water at ambient temperature (pH 0.93 - 1.71).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
