Registration Dossier
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EC number: 945-069-6 | CAS number: -
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 06 June 2017 to 25 August 2017
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- unsuitable test system
- Remarks:
- The test method is suitable for substance with a vapour pressure between 10E02 Pa to 10E05 Pa. Based on information on structural analogues and the available QSARs this method is not the correct method to be followed and is expected to provide non-reliable results
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- no
- Type of method:
- isoteniscope
- Remarks:
- The test method used is suitable for substances with a vapour pressure between 1E02 Pa to 1E05 Pa. Based on information on structural analogues and the available QSARs this method is expected to provide non-reliable results
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 141 Pa
- Test no.:
- #2
- Temp.:
- 20 °C
- Vapour pressure:
- 145 Pa
- Test no.:
- #3
- Temp.:
- 20 °C
- Vapour pressure:
- 143 Pa
- Conclusions:
- The vapour pressure of the substance based on 3 measurements is 143 Pa, when using the isoteniscope method
- Executive summary:
In a study using the isoteniscope method, the vapour pressure of the substance at 20 °C was assessed in 3 independent experiments to be 143 Pa. The test method used is suitable for substances with a vapour pressure between 1E02 Pa to 1E05 Pa. Based on information on structural analogues and the available QSARs this method is not the correct method to be followed and is expected to provide non-reliable results
Reference
Description of key information
In a study using the isoteniscope method, the vapour pressure of the substance at 20 °C was assessed in 3 independent experiments to be 143 Pa. The test method used is suitable for substances with a vapour pressure between 1E02 Pa to 1E05 Pa. Based on information on structural analogues and the available QSARs this method is not the correct method to be followed and the results are therefore considered not reliable.
QSAR models on two representative structures (based on the measured boiling point) gave a vapour pressure between 0.73 and 0.79 Pa.
Key value for chemical safety assessment
- Vapour pressure:
- 0.76 Pa
- at the temperature of:
- 25 °C
Additional information
Based on this information the vapour pressure of the substance is set at the mean of the 2 QSAR values.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
