3-aminophenol

Guidance on Safe Use

First-aid measures

4.1 Description of first aid measures

General advice

Move out of dangerous area. Place and transport victim in stable position (lying sideways). Remove contaminated clothing immediately and dispose of safely.

Inhalation

Move to fresh air. Keep patient warm and at rest. Call a physician or poison control center immediately.

Skin contact

Wash off thoroughly with plenty of soap and water, if available with polyethyleneglycol 400, subsequently rinse with water. If symptoms persist, call a physician.

Eye contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. If eye irritation or redness persists, see an ophthalmologist.

Ingestion

Rinse mouth. Do NOT induce vomiting. Call a physician or poison control center immediately.

4.2 Most important symptoms and effects, both acute and delayed

Symptoms

Local: Breathing difficulties

Systemic: Cyanosis, Dizziness, Weakness

4.3 Indication of any immediate medical attention and special treatment needed

Risks

Watch victim for at least 48 hours because of possible delayed signs of poisoning.

Treatment

Treat symptomatically. There is no specific antidote.

Fire-fighting measures

SECTION 5: FIREFIGHTING MEASURES

5.1 Extinguishing media

Suitable

Foam, Dry chemical, Carbon dioxide (CO2), Water spray

Unsuitable

High volume water jet

5.2 Special hazards arising from the substance or mixture

Dangerous gases are evolved in the event of a fire., In the event of fire the following may be released:, Carbon monoxide (CO), Carbon dioxide (CO2), Nitrogen oxides (NOx)

5.3 Advice for firefighters

Special protective equipment for firefighters

In the event of fire and/or explosion do not breathe fumes. In the event of fire, wear self-contained breathing apparatus.

Further information

Contain the spread of the fire-fighting media. Do not allow run-off from fire fighting to enter drains or water courses.

Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Precautions

Avoid dust formation. Avoid contact with spilled product or contaminated surfaces. Use personal protective equipment. Remove all sources of ignition.

6.2 Environmental precautions

Do not allow to get into surface water, drains and ground water.

6.3 Methods and materials for containment and cleaning up

Methods for cleaning up

Use mechanical handling equipment. Clean contaminated floors and objects thoroughly, observing environmental regulations. Collect and transfer the product into a properly labelled and tightly closed container.

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.  

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

SECTION 7: HANDLING AND STORAGE

7.1 Precautions for safe handling

Advice on safe handling

Avoid dust formation. Use only in area provided with appropriate exhaust ventilation.

Advice on protection against fire and explosion

Dust may form explosive mixture in air. Keep away from heat and sources of ignition.

Hygiene measures

Avoid contact with skin, eyes and clothing. Keep working clothes separately. Wash hands before breaks and immediately after handling the product. Remove soiled clothing immediately and clean thoroughly before using again. Garments that cannot be cleaned must be destroyed (burnt).

7.2 Conditions for safe storage, including any incompatibilities

Requirements for storage areas and containers

Store in original container. Keep containers tightly closed in a dry, cool and well-ventilated place. Store in a place accessible by authorized persons only. Keep away from direct sunlight. Protect from frost.

Advice on common storage

Keep away from food, drink and animal feedingstuffs.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN 2512

Shipping information

Proper shipping name and description:

AMINOPHENOLS (O-, M-, P-)

Chemical name:

M-AMINOPHENOL

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging 6.1+EHS,
Bulk 6.1 + EHS,
HazID 60,
EAC 2X

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN 2512

Shipping information

Proper shipping name and description:

AMINOPHENOLS (O-, M-, P-)

Chemical name:

M-AMINOPHENOL

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging 6.1+EHS,
Bulk 6.1 + EHS,
HazID 60

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN2512

Shipping information

Proper shipping name and description:

AMINOPHENOLS (O-, M-, P-)

Chemical name:

M-AMINOPHENOL

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group III: Substances presenting low danger

EmS code:

F-A

S-A

Labels:

Packaging 6.1,
Bulk 6.1

Marine pollutant

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN 2512

Shipping information

Proper shipping name and description:

AMINOPHENOLS (O-, M-, P-)

Chemical name:

M-AMINOPHENOL

Language:

English

Class or division:

Class 6: Toxic and infectious substances; Division 6.1

Packing group:

Packing group III: Substances presenting low danger

Labels:

Packaging 6.1

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with  REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4).  Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each manufacturing site.  

 

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Processor/User of the Registrant’s intermediate.

 

8.2 Exposure controls

Respiratory protection

Wear respirator with a particle filter mask (protection factor 20) conforming to European Norm EN149FFP3 or EN140P3 or equivalent.

Respiratory protection should only be used to control residual risk of short duration activities, when all reasonably practicable steps have been taken to reduce exposure at source e.g. containment and/or local extract ventilation. Always follow respirator manufacturer's instructions regarding wearing and maintenance.

Hand protection

Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time.

Wash gloves when contaminated. Dispose of when contaminated inside, when perforated or when contamination outside cannot be removed.

 

Material	Nitrile rubber
Rate of permeability	> 480 min
Glove thickness	> 0,4 mm
Protective index	Class 6
Directive	Protective gloves complying with EN 374.

 

Eye protection

Wear goggles (conforming to EN166, Field of Use = 5 or equivalent).

Skin and body protection

Wear standard coveralls and Category 3 Type 4 suit.

If there is a risk of significant exposure, consider a higher protective type suit.

Wear two layers of clothing wherever possible. Polyester/cotton or cotton overalls should be worn under chemical protection suit and should be professionally laundered frequently.

If chemical protection suit is splashed, sprayed or significantly contaminated, decontaminate as far as possible, then carefully remove and dispose of as advised by manufacturer.

Stability and reactivity

10.1 Reactivity

Thermal decomposition

Stable under normal conditions.

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Dust may form explosive mixture in air.

10.4 Conditions to avoid

Extremes of temperature and direct sunlight.

10.5 Incompatible materials

Oxidizing agents, Acids, Acid chlorides, Acid anhydrides

10.6 Hazardous decomposition products

Thermal decomposition can lead to release of: Toxic gases/vapours

Disposal considerations

During the whole life cycle of the substance all necessary measures in accordance to art. 18(4) of (EC) 1907/2006 are undertaken. The substance is handled under strictly controlled conditions.

No material is emitted into the soil.

No residues from the production plant are deposited in landfills.

Organic waste is thermally disposed of in industrial incineration plants operating under legal permit.