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Diss Factsheets
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EC number: 824-801-7 | CAS number: 1093628-27-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of Witconate P-1460 to the fresh water fish Dania rerio (zebra fish) was tested under static conditions for 96 hours in accordance with OECD Guidelines for testing of chemicals, 203: Fish, acute toxicity test (7/1992) and EEC Directive 79/831, Annex V, part C: Methods for the determination of ecotoxicity, part C.1. Acute toxicity to fish (update 11/1989) The test was performed in compliance with Good Laboratory Practice (GLP).
Witconate P-1460 is miscible in water. A preliminary test on Dania rerio, performed as a non-GLP test, showed no lethality at 1 mg/L but 2 out of the three fish were lying on the bottom after 96 hours of testing. At 10 mg/L 100 % death was observed after 24 hours. At 100 mg/L 100% death was observed after 4 hours.The results of the definitive test show that the test substance had 100% lethal effect at 9.37 mg/L of Witconate P-1460 after 24 hours of testing, but no lethal or sub-lethal effects were observed at the other test concentrations of respectively 0.4, 0.88 1.94 and 4.26 mg/L.
Based on the test results a NOEC (no observed effect concentration) and the LOEC (lowest observed effect concentration) (0-96h) of Witconate P-1460 was derived of 4.26 mg/Land 9.37 mg/L respectively. Based on the available data an LC50 was calculated of 6.32 mg/L. The LC100 observed after 96 hours of testing 9.37 mg/L Witconate P-1460. No other sub-lethal effects were observed in the tested concentrations.
The results of the chemical analyses show that the average observed test substance concentrations during the test differed less than 20% from the nominal test concentrations. The results are therefore presented based on their nominal concentrations. The average observed test substance concentrations were found to be all higher than the nominal concentrations.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6.32 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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