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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 947-523-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.406 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 4.06 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 40.6 ng/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 0.406 µg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.501 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 50.1 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 100 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The aquatic toxicity of the test item was assessed by read-across from a structural analogue (DV6850), which was tested in short-term toxicity tests to fish, daphnia and algae. All tests had the highest reliability rating (Klimisch code 1). Fish was the most sensitive organism with an LC50 of 0.406 mg/L, followed by daphnia with an EC50 of 33.6 mg/L. For algae, ErC50 and NOEC of 85.4 mg/L and 42.9 mg/L were reported, respectively.
The results indicate that fish are the most sensitive organism to the target substance, indicating that it is very toxic.
Furthermore, the effect of DV6850 on the respiration rate of activated sludge was assessed in a valid GLP study (Klimisch 1). DV6850 was reported to have had no effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The NOEC was reported as 100 mg/L, the highest concentration tested and the EC50 was reported as > 100 mg/L.
A read-across justification document has been prepared in compliance with the RAAF guidance from ECHA, and is attached to Section 13.
Conclusion on classification
Boundary composition.001 (Composition of C18:1 amidopropyl betaine containing≥0.1% and < 10% C18:1 aminopropyl amide)
The target substance (TS) is classified as "hazardous to the aquatic environment", Category Acute 1, Chronic 2, according to Commission Regulation (EU) No 286/2011 of 10 March 2011 (second amendment of CLP regulation), as the 96 hour LC50 for fish is lower than 1 mg/L and the amide impurity (N-[3-(dimethylamino)propyl]aleamide, CAS#109-28-4, EC#203-661-5) is classified as Category Acute 1, Chronic 1.
Boundary composition.002_(Composition of C18:1 amidopropyl betaine containing < 0.1% C18:1 aminopropyl amide)
The target substance (TS) is classified as "hazardous to the aquatic environment", Category Acute 1, according to Commission Regulation (EU) No 286/2011 of 10 March 2011 (second amendment of CLP regulation), as the 96 hour LC50 for fish is lower than 1 mg/L. It is not classified for chronic effects as the TS is readily biodegradable (by read-across) and has experimental log kow of 0.8.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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