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Diss Factsheets
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EC number: 208-066-4 | CAS number: 507-20-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2017-08-25 to 2017-11-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- differential scanning calorimetry
- Key result
- Boiling pt.:
- 51 °C
- Atm. press.:
- 1 013.25 hPa
- Decomposition:
- no
- Conclusions:
- The boiling point of the test item was determined to be 51.0 °C at 1013.25 hPa.
- Executive summary:
A study was performed according to OECD TG 103 and Commission Regulation (EC) No. 440/2008 method A.2. in order to determine the boiling point of the test item by using differential scanning calorimetry method (DSC). Two DSC measurements were performed in open crucibles. An endothermal effect was observed in the temperature range of approximately 20 to 90 °C. The mass loss after the DSC measurements was 100 %. Due to the ambiguous onset of the endothermic effect it was assumed that the vapour pressure of the test item influenced the measurements. Hence the determination of the vapour pressure was used for evaluation of the boiling point. Using the Antoine constants A, B and C and the pressure of 1013.25 hPa the boiling temperature of the test item was determined to be 51.0 °C.
Reference
Individual results (DSC measurement)
Two DSC measurements in open glass crucibles showed an exothermal effect in the temperature range of 20 - 90 °C. No further exothermic or endothermic effects were observed up to the final temperature (200 °C). The mass loss after the DSC measurements amounted to 100 %.
The results of the DSC measurements are summarized in table 1.
Table 1: Boiling point (DSC measurement)
Ident No. | Test item (mg) |
Starting temperature (°C) |
Final test (°C) |
Temperature range (endo- thermal) (°C) | Crucible | Observations after the measurement |
36546 | 16.78 | 0 | 200 | 25 - 90 | open glass | mass loss: 100% |
36549 | 15.29 | 5 | 200 | 20 - 90 | open glass | mass loss: 100% |
According to DSC measurements the test item had a boiling range of 20 - 90 °C. In both DSC measurements an ambiguous onset of the endothermal effect was observed. Possibly the DSC measurements were influenced by the vapour pressure of the test item (see also mass loss during the open glass measurement with the final temperature of 10 °C for the melting point. Due to the ambiguous onset of the endothermal effect the data of the determination of the vapour pressure was used for the evaluation of the boiling point/range of the test item.
Calculation of boiling point via Antoine parameters
With the dynamic method the vapour pressure was measured in the temperature range of 10 °C to 47 °C. Using the Antoine constants A, B and C and the pressure of 1013.25 hPa the boiling temperature is calculated to be 50.9 °C (see below table 2).
Table 2: Antoine parameters and extrapolated vapour pressures
log (p/hPa) = A + B/(C+T[°C]) | p (hPa) | T (°C) |
A = 5.346 | 1013.25 | 51.0 |
B =-411.1 |
||
C = 124.7 |
The test item had a mean boiling point at atmospheric pressure (1013.25 hPa) of 51.0 °C.
Description of key information
The boiling point of the test item was determined to be 51.0 °C at 1013.25 hPa.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 51 °C
Additional information
A study was performed according to OECD TG 103 and Commission Regulation (EC) No. 440/2008 method A.2. in order to determine the boiling point of the test item by using differential scanning calorimetry method (DSC). Two DSC measurements were performed in open crucibles. An endothermal effect was observed in the temperature range of approximately 20 to 90 °C. The mass loss after the DSC measurements was 100 %. Due to the ambiguous onset of the endothermic effect it was assumed that the vapour pressure of the test item influenced the measurements. Hence the determination of the vapour pressure was used for evaluation of the boiling point. Using the Antoine constants A, B and C and the pressure of 1013.25 hPa the boiling temperature of the test item was determined to be 51.0 °C (reference 4.3-1).
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