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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06-2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
not specified
GLP compliance:
not specified
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
5-(dithiolan-3-yl)valeric acid
EC Number:
214-071-2
EC Name:
5-(dithiolan-3-yl)valeric acid
Cas Number:
1077-28-7
Molecular formula:
C8H14O2S2
IUPAC Name:
5-(1,2-dithiolan-3-yl)pentanoic acid
impurity 1
Reference substance name:
unknown
IUPAC Name:
unknown
impurity 2
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
dihydrogen oxide
Test material form:
solid: bulk
Details on test material:
This composition is the usual techical grade of AlzChem AG. It will be used when test substance has this composition (or is very closed) or no specific information is available
Specific details on test material used for the study:
Batch: 717841

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
ca. 59 °C
Atm. press.:
ca. 1 013 hPa
Decomposition:
no

Applicant's summary and conclusion

Conclusions:
Alpha-lipoic acid has a melting point of 59 °C at 1013 hPa.
Executive summary:

The melting temperature from a-Lipoic acid is measured by Differential-Scanning-Calorimetry. The test is according to EC 440/2008 A.1. The substance showed a melting temperature of T = 59 °C.