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EC number: 238-942-1 | CAS number: 14871-79-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- experimental data of read across substances
- Justification for type of information:
- Data for the target chemical is summarized based on the closely related read across chemicals.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- WoE report was prepared based on toxicity study of test chemical to aquatic algae.
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Chlorococcales and Skeletonema costatum
- Details on test organisms:
- 2. Details on test organisms
TEST ORGANISM
- Common name: Green Algae Order
3. Details on test organisms
TEST ORGANISM
- Common name: Diatom - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- Toxicity of test chemical was also studied after providing exposure period of 24 hrs.
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Assimilation efficiency
- Remarks on result:
- other: Other details not known
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 500 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Reduction in Chlorophyll A concentration
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- By applying weight of evidence approach the EC 50 value if test chemical is expected to be in range from 500 to 1000 mg/L after exposure of test chemical for 24-96 hrs. The EC50 value indicates that the substance is likely to be nonhazardous to aquatic algae and cannot be classified as per the CLP classification criteria.
- Executive summary:
Summarized studies of the test chemical on the growth and other biological activity of aquatic algae were studied. The studies are as mentioned below:
Aim of this study was to investigate the effect of test chemical on the growth of aquatic algae. Test conducted under the static system continued for 24 hrs. Based on the effects observations on assimilation efficiency of Chlorococcales (Green Algae Order) after the exposure of test chemical for 24 hrs, the EC50 was determine to be 1000 mg/l. Thus on the basis of EC50 value, chemical was consider to be nontoxic and can be consider to be not classified as per the CLP classification criteria.
Similar study was also performed to determine the toxicity of test chemical. Principle of this study was to investigate the effect of test chemical on the growth of aquatic algae and cyanobacteria. Test conducted under the static system for 96 hrs of exposure with chemical. Based on the reduction in Chlorophyll A concentration of Skeletonema costatum (Diatom) by the chemical exposure for 96 hrs, the EC50 was determine to be 500 mg/l. Thus based on the EC50 value, chemical was consider to be nontoxic and can be consider to be not classified as per the CLP classification criteria.
Thus based on the overall studies for the test chemical from various sources, it is concluded that the test chemical was nontoxic and not classified as per the CLP classification criteria.
Reference
Description of key information
By applying weight of evidence approach the EC 50 value if test chemical is expected to be in range from 500 to 1000 mg/L after exposure of test chemical for 24-96 hrs. The EC50 value indicates that the substance is likely to be nonhazardous to aquatic algae and cannot be classified as per the CLP classification criteria
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 000 mg/L
Additional information
Summarized studies of the test chemical and closest similar read across chemical on the growth and other biological activity of aquatic algae were studied. The studies are as mentioned below:
Aim of this study was to investigate the effect of test chemical on the growth of aquatic algae. Test conducted under the static system continued for 24 hrs. Based on the effects observations on assimilation efficiency of Chlorococcales (Green Algae Order) after the exposure of test chemical for 24 hrs, the EC50 was determine to be 1000 mg/l. Thus on the basis of EC50 value, chemical was consider to be nontoxic and can be consider to be not classified as per the CLP classification criteria.
Similar study was also performed to determine the toxicity of test chemical. Principle of this study was to investigate the effect of test chemical on the growth of aquatic algae and cyanobacteria. Test conducted under the static system for 96 hrs of exposure with chemical. Based on the reduction in Chlorophyll A concentration of Skeletonema costatum (Diatom) by the chemical exposure for 96 hrs, the EC50 was determine to be 500 mg/l. Thus based on the EC50 value, chemical was consider to be nontoxic and can be consider to be not classified as per the CLP classification criteria.
Thus based on the overall studies for the test chemical from various sources, it is concluded that the test chemical was nontoxic and not classified as per the CLP classification criteria.
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