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EC number: 276-123-0 | CAS number: 71873-46-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to aquatic invertebrates
EC50 (24h) > 100 mg/l (nominal)
Toxicity to aquatic plants other than algae
ErC50 (7d): 11.29 mg/l (geom. mean), based on frond number
Additional information
Short-term toxicity to aquatic invertebrates
The acute toxicity of the test substance to Daphnia magna was investigated over a period of 24 hours, following the OECD guideline 202, part I (1984). No chemical analysis of the test substance concentration was conducted. No deaths occurred at the nominal concentration of 100 mg/l; 10 % of mortality was observed in one of the two blank controls. The EC0 was identified to be 100 mg/l. Test medium appeared to be blue solution.
Toxicity to aquatic plants other than algae
The phytotoxicity of the test item on the freshwater aquatic plant Lemna gibba was assessed in accordance with method and procedures outlined into the OECD guideline 221.
In the main test, exponentially growing cultures of Lemna gibba were exposed to nominal concentrations 5.0, 10.0, 20.0, 40.0, 80.0 and 160 mg/l of the test item, over a period of 7 days in a static system under defined conditions.
The measured concentrations deviated more than 20 % from the nominal during the experiment in each concentration, therefore, biological results are based on the geometric mean of the measured test item concentrations.
The average specific growth rate, as well as yield, was statistically significantly different from the control group at the concentrations of 1.29, 2.54, 5.49, 10.97, 23.69 and 32.70 mg/l, based on on frond number, dry and fresh weight.
NOEr/yC (7d): < 1.29 mg/l, based on frond number, dry and fresh weight
LOEr/yC (7d): 1.29 mg/l, based on frond number, dry and fresh weight
ErC50 (7d): 11.29 mg/l (95 % confidence limits: 9.211 – 14.089 mg/l), based on frond number
ErC50 (7d): 7.47 mg/l (95 % confidence limits: 6.058 – 9.212 mg/l), based on dry weight
ErC50 (7d): 8.61 mg/l (95 % confidence limits: 7.468 – 9.956 mg/l), based on fresh weight
EyC50 (7d): 4.68 mg/l (95 % confidence limits: 4.025 – 5.383 mg/l), based on frond number
EyC50 (7d): 3.06 mg/l (95 % confidence limits: 2.535 – 3.605 mg/l), based on dry weight
EyC50 (7d): 3.57 mg/l (95 % confidence limits: 3.228 – 3.924 mg/l), based on fresh weight
Justification for classification or non-classification
According to the CLP Regulation (EC n. 1272/2008), Part 4: Environmental Hazards, the substances can be classified for hazardous to the aquatic environment when the following criteria are met:
A )Acute (short-term) aquatic hazard
Category Acute 1: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) ≤ 1 mg/l
B) Long-term aquatic hazard
(iii) Substances for which adequate chronic toxicity data are not available and the substance is not rapidly degradable and/or the experimentally determined BCF ≥ 500 (or, if absent, the log K ow ≥ 4).
Category Chronic 1: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) ≤ 1 mg/l
Category Chronic 2: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants)> 1 to ≤10 mg/l
Category Chronic 3: 96 hr LC 50 (for fish) and/or 48 hr EC 50 (for crustacea) and/or 72 or 96 hr ErC 50 (for algae or other aquatic plants) > 10 to ≤ 100 mg/l
In the Lemna gibba study an ErC50 of 11.29 mg/l was found therefore the substance has been classified as toxic to aquatic compartment Category 3 according to the CLP Regulation (EC 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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